Weinstein R S, New K D, Sappington L J
Medical College of Georgia, Department of Medicine, Augusta 30912.
Calcif Tissue Int. 1991 Nov;49(5):313-6. doi: 10.1007/BF02556252.
Radial diaphyseal bone mineral density (BMD) was measured at the standard one-third site by dual-energy X-ray absorptiometry (DEXA) and by 125I single photon absorptiometry (SPA) in 70 consecutive subjects, aged 12-86 years, with metabolic disorders of the skeleton. Each patient was measured once by the DEXA (Hologic QDR-1000) instrument and four times by the SPA (Norland 2780) instrument on the same day by one or the other of 2 technicians. The DEXA and SPA measurements were linearly related and highly correlated (r = 0.975, P less than 0.0001) over a range from severe osteopenia to high normal BMD. Ninety-five percent of the variation in the BMD determined by SPA was accounted for by DEXA, so that the BMD(SPA) = 1.035 +/- 0.027 (SEM) x BMD(DEXA)-0.007 +/- 0.019 (SEM). This permits continued use of previously accumulated SPA data-bases. The coefficient of variation for repeat measurements by DEXA was 1.2% and by SPA 1.6%. Examination time by DEXA was 6-7 minutes, about 45% shorter than the corresponding SPA determinations. DEXA is the superior method for evaluation of the radius, as it provides faster and more precise measurements in clinical practice.
采用双能X线吸收法（DEXA）和¹²⁵I单光子吸收法（SPA），在标准的桡骨干三分之一部位，对70例年龄在12 - 86岁、患有骨骼代谢紊乱的连续受试者进行桡骨干骨矿物质密度（BMD）测量。每位患者由2名技术人员中的1名，在同一天使用DEXA（Hologic QDR - 1000）仪器测量1次，使用SPA（Norland 2780）仪器测量4次。在从严重骨质减少到高正常骨密度的范围内，DEXA和SPA测量值呈线性相关且高度相关（r = 0.975，P < 0.0001）。SPA测定的骨密度变化的95%可由DEXA解释，因此BMD(SPA) = 1.035 ± 0.027（标准误）×BMD(DEXA) - 0.007 ± 0.019（标准误）。这使得先前积累的SPA数据库能够继续使用。DEXA重复测量的变异系数为1.2%，SPA为1.6%。DEXA的检查时间为6 - 7分钟，比相应的SPA测定时间短约45%。在临床实践中，DEXA是评估桡骨的更佳方法，因为它能提供更快、更精确的测量结果。
