Htwe Tin Han, Mushtaq Adnan, Robinson Sherry B, Rosher Richard B, Khardori Nancy
Division of Infectious Diseases, Southern Illinois University School of Medicine, Post Box 19636, Springfield, IL 62794-9636, USA.
Infect Dis Clin North Am. 2007 Sep;21(3):711-43, ix. doi: 10.1016/j.idc.2007.07.006.
Many functional, demographic, and immunologic changes associated with aging are responsible for increasing the incidence and severity of infectious diseases in the elderly. Management is complicated by age-related organ system changes. Because many of the elderly are on multiple medications for underlying illnesses, antimicrobial therapy needs to be chosen keeping drug interactions and adverse events in mind. Common infections seen in the elderly are infections of skin and soft tissue, urinary tract, respiratory tract, and gastrointestinal tract. Organized and well-funded programs to address infectious disease issues in the elderly are the only way to improve care.
许多与衰老相关的功能、人口统计学和免疫学变化导致老年人传染病的发病率和严重程度增加。与年龄相关的器官系统变化使治疗变得复杂。由于许多老年人因基础疾病而服用多种药物,选择抗菌治疗时需要考虑药物相互作用和不良事件。老年人常见的感染包括皮肤和软组织感染、尿路感染、呼吸道感染和胃肠道感染。有组织且资金充足的项目来解决老年人的传染病问题是改善护理的唯一途径。