Agarwal Shipra, Rishi Arvind, Suri Vaishali, Sharma M C, Satyarthi G D, Garg Ajay, Sarkar Chitra
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Clin Neurol Neurosurg. 2007 Dec;109(10):888-91. doi: 10.1016/j.clineuro.2007.07.026. Epub 2007 Sep 10.
Primary intracranial squamous cell carcinoma is extremely rare, with most of the cases arising from malignant transformation of an epidermoid or a dermoid cyst. We report here a case of a 45-year-old male patient who presented with 1-month history of intermittent headache and recent onset of altered sensorium. Imaging revealed a midline posterior fossa mass lesion compressing the fourth ventricle and causing hydrocephalus. A provisional diagnosis of dermoid cyst was considered. Histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity.
原发性颅内鳞状细胞癌极为罕见，大多数病例由表皮样囊肿或皮样囊肿恶变而来。我们在此报告一例45岁男性患者，有1个月间歇性头痛病史，近期出现意识改变。影像学检查显示后颅窝中线有一肿块病变，压迫第四脑室并导致脑积水。初步诊断考虑为皮样囊肿。组织病理学检查显示为鳞状细胞癌，可能起源于潜在的表皮样囊肿。因其罕见性而报告此病例。
