Kalechstein Ari D, Fong Timothy, Rosenthal Richard J, Davis Alice, Vanyo Heidi, Newton Thomas F
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.
J Neuropsychiatry Clin Neurosci. 2007 Summer;19(3):298-303. doi: 10.1176/jnp.2007.19.3.298.
Using tests that are frequently administered by neuropsychologists, the authors investigated whether pathological gambling is associated with frontal lobe abnormalities. The sample comprised 10 pathological gamblers, 25 methamphetamine-dependent subjects, and 19 matched comparison subjects. The pathological gamblers and methamphetamine-dependent subjects performed significantly less well than comparison subjects, and the gamblers' test scores were comparable to those of the methamphetamine-dependent participants. The overall magnitude of the effect size was large. These findings demonstrate that the severity of frontal lobe dysfunction in pathological gambling is similar to that observed in methamphetamine-dependent individuals on frequently used clinical measures.
作者使用神经心理学家常用的测试，调查病理性赌博是否与额叶异常有关。样本包括10名病理性赌博者、25名甲基苯丙胺依赖者和19名匹配的对照对象。病理性赌博者和甲基苯丙胺依赖者的表现明显不如对照对象，且赌博者的测试分数与甲基苯丙胺依赖参与者的分数相当。效应量的总体大小很大。这些发现表明，在常用的临床测量中，病理性赌博中额叶功能障碍的严重程度与甲基苯丙胺依赖个体中观察到的相似。
