Hamstra Daniel A, Rehemtulla Alnawaz, Ross Brian D
Department of Radiation Oncology, The Center for Molecular Imaging, University of Michigan Medical Center, Ann Arbor, MI 48109-2200, USA.
J Clin Oncol. 2007 Sep 10;25(26):4104-9. doi: 10.1200/JCO.2007.11.9610.
Imaging of response to oncology treatments, either on clinical protocol or as part of standard practice, is a complicated process that has evolved during the last 10 years due to the improvement of existing imaging technologies and the introduction of newer modalities. Diffusion magnetic resonance imaging is a technique that measures the mobility of water within tissues and, as such, may function as a surrogate marker for both tissue cellularity and response to treatment that occur earlier than usual measures of tumor response. This review highlights the development of this technique and the state of current clinical understanding of its utility.
对肿瘤治疗反应的成像，无论是作为临床方案的一部分还是作为标准实践的一部分，都是一个复杂的过程。在过去十年中，由于现有成像技术的改进和更新模式的引入，这一过程不断发展。扩散磁共振成像是一种测量组织内水分子运动的技术，因此，它可以作为组织细胞密度和治疗反应的替代标志物，其出现时间比通常的肿瘤反应测量指标更早。这篇综述重点介绍了该技术的发展以及目前临床对其效用的理解状况。
