Shanbhogue Alampady Krishna Prasad, Karnad Anand B, Prasad Srinivasa R
Department of Radiology, University of Texas HSC at San Antonio, San Antonio, TX 78229, USA.
J Comput Assist Tomogr. 2010 Jul;34(4):479-84. doi: 10.1097/RCT.0b013e3181db2670.
Quantification of tumor burden and assessment of changes in tumor size after chemotherapy are commonly performed to evaluate treatment response in oncology trials. Validation and adoption of different criteria have been attempted in the past to achieve uniformity in scanning techniques and measurement metrics so that comparison of different oncological trials is feasible. Response assessment of solid tumors is usually consisted of either bidimensional (World Health Organization criteria) or unidimensional (Response Evaluation Criteria in Solid Tumors [RECIST] guidelines) measurement of tumors before and after chemotherapy. RECIST 1.1 criteria have been recently published. In this article, we try to provide a comprehensive review of the tumor response evaluation guidelines that were recently updated in attempts to overcome limitations of the previous criteria as well as incorporate recent advances in imaging techniques.
在肿瘤学试验中，通常会对肿瘤负荷进行量化，并评估化疗后肿瘤大小的变化，以评估治疗反应。过去曾尝试验证和采用不同的标准，以实现扫描技术和测量指标的统一，从而使不同肿瘤学试验的比较成为可能。实体瘤的反应评估通常包括化疗前后肿瘤的二维测量（世界卫生组织标准）或一维测量（实体瘤反应评估标准[RECIST]指南）。RECIST 1.1标准最近已发布。在本文中，我们试图对最近更新的肿瘤反应评估指南进行全面综述，以克服先前标准的局限性，并纳入成像技术的最新进展。
