Starzyńska Teresa
Department of Gastroenterology, Pomeranian Medical Academy, Szczecin, Poland.
Dig Dis. 2007;25(3):222-4. doi: 10.1159/000103889.
Molecular epidemiology refers to the incorporation of molecular techniques in epidemiological studies. There are different biomarkers in cancer research used for molecular epidemiology including markers of exposure, markers of dose, susceptibility, treatment response, prognosis, altered structure/function and cancer type. Selected markers, especially those of exposure and susceptibility, are described in an example of gastric cancer. Clinical significance of molecular epidemiology is discussed.
分子流行病学是指将分子技术应用于流行病学研究。癌症研究中有不同的生物标志物用于分子流行病学,包括暴露标志物、剂量标志物、易感性标志物、治疗反应标志物、预后标志物、结构/功能改变标志物和癌症类型标志物。在一个胃癌实例中描述了选定的标志物,尤其是暴露标志物和易感性标志物。讨论了分子流行病学的临床意义。