De Rosa G, Mignogna C
Department of Biomorphological and Functional Sciences, Pathology Section, Federico II University of Naples, Italy.
Reumatismo. 2007;59 Suppl 1:46-8. doi: 10.4081/reumatismo.2007.1s.46.
Psoriasis is a common, chronic, relapsing, papulo-squamous dermatitis, with overlying silvery scales. The scalp, sacral region, and extensor surfaces of extremity are commonly involved, even if flexural and intertriginous areas may be affected in the so-called "inverse psoriasis". Involvement of nails is frequent. Oral lesions (geographic stomatitis and/or glossitis) are commonly described. 5-8% of psoriatic patients develop arthritis. Interphalangeal joints are characteristically involved, but large joints are also affected. From a histological point of view, psoriasis is a dynamic dermatosis that changes during the evolution of an individual lesion; we can classify it in an early stage, advanced stage, and later lesions. Lesions are usually diagnostic only in early stages or near the margin of advancing plaques. Munro microabscesses and Kogoj micropustoles are diagnostic clues of psoriasis, but they aren't always present. All other features can be found in numerous eczematous dermatitis.
银屑病是一种常见的慢性复发性丘疹鳞屑性皮肤病，有银白色鳞屑覆盖。头皮、骶尾部及四肢伸侧常受累，即便在所谓的“反向银屑病”中屈侧和间擦部位也可能受到影响。指甲受累很常见。常描述有口腔损害（地图舌炎和/或舌炎）。5-8%的银屑病患者会发展为关节炎。指间关节是典型受累部位，但大关节也会受到影响。从组织学角度看，银屑病是一种动态性皮肤病，在单个皮损演变过程中会发生变化；我们可以将其分为早期、进展期和后期皮损。皮损通常仅在早期或进展斑块边缘附近具有诊断意义。Munro微脓肿和Kogoj微脓疱是银屑病的诊断线索，但并非总是存在。所有其他特征在众多湿疹性皮炎中也可出现。
