Paul V J, Fenical W
Science. 1983 Aug 19;221(4612):747-9. doi: 10.1126/science.221.4612.747.
Halimedatrial, a structurally unprecedented diterpenoid trialdehyde, has been identified as the major secondary metabolite in six species of the calcareous reef-building alga Halimeda. In laboratory bioassays, halimedatrial is toxic toward reef fishes, significantly reduces feeding in herbivorous fishes, and has cytotoxic and antimicrobial activities. The widespread occurrence of halimedatrial and its potent biological activities suggest that this metabolite represents a chemical defense adaptation in this pantropical marine alga.
海木耳醛是一种结构前所未有的二萜醛，已被确定为六种造礁钙质海藻海木耳属中的主要次生代谢产物。在实验室生物测定中，海木耳醛对珊瑚礁鱼类有毒，能显著减少草食性鱼类的摄食量，并且具有细胞毒性和抗菌活性。海木耳醛的广泛存在及其强大的生物活性表明，这种代谢产物代表了这种泛热带海洋藻类的一种化学防御适应机制。
