Formisano R, Falaschi P, Cerbo R, Proietti A, Catarci T, D'Urso R, Roberti C, Aloise V, Chiarotti F, Agnoli A
1st Chair Department of Neurological Sciences, La Sapienza, University of Rome, Italy.
Eur J Clin Pharmacol. 1991;41(1):69-71. doi: 10.1007/BF00280110.
Serum prolactin is increased during chronic flunarizine treatment of patients suffering from migraine. In order to clarify the role of calcium in control of the secretion of anterior pituitary hormones, a study has now been made of the effects of chronic nimodipine and propranolol treatment of migraine patients on prolactin (PRL), luteinizing hormone (LH) and growth hormone (GH) levels. 11 patients were treated with nimodipine and 8 with propranolol for four months. A statistically significant reduction in the frequency of the attacks was demonstrated in both groups. No significant change was found in the hormones levels during nimodipine treatment.
在对偏头痛患者进行慢性氟桂利嗪治疗期间，血清催乳素会升高。为了阐明钙在控制垂体前叶激素分泌中的作用，现已对偏头痛患者进行慢性尼莫地平和普萘洛尔治疗对催乳素（PRL）、黄体生成素（LH）和生长激素（GH）水平的影响展开了一项研究。11名患者接受了尼莫地平治疗，8名患者接受了普萘洛尔治疗，为期四个月。两组患者的发作频率均有统计学意义的降低。在尼莫地平治疗期间，未发现激素水平有显著变化。
