Ushio Y, Abe H
Research Institute of Oriental Medicine, Kinki University, Osaka, Japan.
Int J Immunopharmacol. 1991;13(5):493-9. doi: 10.1016/0192-0561(91)90068-i.
The effects of saikosaponin-d, isolated from Bupleurum Radix, on phagocytosis and spreading of mouse peritoneal macrophages were investigated. Macrophages from saikosaponin-d-treated mice showed a significant increase in spreading activity followed by an increase in phagocytic activity. An intense distribution of microfilaments and microtubules was also observed in these macrophages by immunofluorescence microscopy.
