禽成髓细胞瘤病毒核心成分中DNA的鉴定
Identification of DNA in the core component of avian myeloblastosis virus.
作者信息
Deeney A O, Stromberg K, Beaudreau G S
出版信息
Biochim Biophys Acta. 1976 May 19;432(3):281-91. doi: 10.1016/0005-2787(76)90137-4.
PMID:178377
Abstract
Avian myeloblastosis virus (AMV) was found to contain DNA associated with the virion. The viral envelope was removed by treating the virus with a nonionic detergent and the DNA was found in the core fraction. These experiments indicate that the DNA associated with tumor virus is not contaminant associated with the viral envelope and suggest that the DNA is part of the internal core component. The DNA from avian myeloblastosis virus has a density of 1.70 g/cm3.
摘要
禽成髓细胞瘤病毒（AMV）被发现含有与病毒粒子相关的DNA。通过用非离子去污剂处理病毒来去除病毒包膜，并且在核心组分中发现了DNA。这些实验表明，与肿瘤病毒相关的DNA不是与病毒包膜相关的污染物，并表明该DNA是内部核心组分的一部分。来自禽成髓细胞瘤病毒的DNA密度为1.70 g/cm³。
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