Lacruz F, Artieda J, Pastor M A, Obeso J A
Department of Neurology, University of Navarra, Pamplona, Spain.
J Neurol Neurosurg Psychiatry. 1991 Dec;54(12):1077-81. doi: 10.1136/jnnp.54.12.1077.
Somaesthetic temporal discrimination (STD) is the ability to perceive as separate two successive somaesthetic stimuli applied to the same or different parts of the body. Paired electrical stimuli were applied to the index finger, using different time-intervals, to study the STD threshold (STDT) in 84 normal subjects and 51 patients with focal cerebral lesions. Abnormal STDT values were found on the affected side of patients with a lesion of the primary somatosensory cortex, and internal capsulethalamus. Lesions which did not produce sensory impairment but caused abnormal STDT were located in the posterior parietal cortex, the head of the caudate nucleus, the putamen, the medial thalamus and the lenticular nucleus. Frontal, temporal and occipital cortex lesions did not produce any abnormality in the STDT, but one patient with a bilateral lesion of the supplementary motor area (SMA) had abnormal STDT. These results indicate that normal perception of two somaesthetic stimuli as separate in time depends not only upon the integrity of the somatosensory pathway and primary somaesthetic cortex, but also of the posterior parietal cortex, SMA and subcortical structures such as the striatum and thalamus.
躯体感觉时间辨别（STD）是指将施加于身体同一部位或不同部位的两个连续躯体感觉刺激分别感知为独立刺激的能力。使用不同的时间间隔，将成对的电刺激施加于食指，以研究84名正常受试者和51名局灶性脑损伤患者的STD阈值（STDT）。在原发性躯体感觉皮层、内囊 - 丘脑损伤患者的患侧发现了异常的STDT值。未产生感觉障碍但导致异常STDT的病变位于顶叶后皮质、尾状核头部、壳核、丘脑内侧和豆状核。额叶、颞叶和枕叶皮质病变未在STDT中产生任何异常，但一名双侧辅助运动区（SMA）病变的患者有异常的STDT。这些结果表明，将两个躯体感觉刺激在时间上分别正常感知不仅取决于躯体感觉通路和原发性躯体感觉皮层的完整性，还取决于顶叶后皮质、SMA以及纹状体和丘脑等皮质下结构的完整性。
