Li H, Xiong S T, Zhang S X, Liu S B, Zou P N, Xiang J P
Department of Surgery, Xiehe Hospital, Tongji Medical University, Wuhan.
J Tongji Med Univ. 1991;11(3):145-9. doi: 10.1007/BF02888125.
Sepsis is a common and occasionally lethal complication of obstructive jaundice. The reasons for the increased susceptibility to infection are not fully understood. This study was conducted to examine lymphocyte subsets and natural killer cells of patients with obstructive jaundice in perioperative period. In these patients, when compared with normal controls, there was a significant reduction in the percentage of Leu 4 (pan T lymphocytes), Leu 3a (T helper cells) and Leu 7 (natural killer cells) before operation, and the immune suppression induced by surgical operation was more marked and persistent.
脓毒症是梗阻性黄疸常见且偶尔致命的并发症。对感染易感性增加的原因尚未完全明确。本研究旨在检测梗阻性黄疸患者围手术期的淋巴细胞亚群和自然杀伤细胞。与正常对照组相比，这些患者术前Leu 4（全T淋巴细胞）、Leu 3a（辅助性T细胞）和Leu 7（自然杀伤细胞）的百分比显著降低，且手术诱导的免疫抑制更为明显和持久。
