Moreno S M, Cukier M, Guerrero G, de Recondo M E, Recondo E F
Carbohydr Res. 1976 Apr;47(2). doi: 10.1016/s0008-6215(00)84193-2.
Levels of nucleotides and sugar nucleotides in embryos of Bufo arenarum at the stages of morula, gastrula, and neurula have been measured. The total amounts of purine nucleoside diphosphates decreased from morula to gastrula, but increased sharply from gastrula to neurula. The levels of ADP followed this pattern, but those of GDP did not change significantly through the three stages. Purine nucleoside triphosphate levels, which had increased immediately after fertilization, remained almost constant through morula, gastrula, and neurula. As with the purine nucleoside diphosphates, the adenine nucleotide decreased from morula to gastrula, and increased from gastrula to neurula. In contrast, the level of GTP showed a sharp maximum at gastrula. The total pyrimidine nucleoside triphosphate did not change significantly from morula through neurula. As in previous stages of development, only uridine sugar nucleotides were detected. A sharp increase of the galactosyl ester of nucleotides was found at gastrula.
已对南美蟾蜍胚胎在桑椹胚、原肠胚和神经胚阶段的核苷酸和糖核苷酸水平进行了测量。从桑椹胚到原肠胚，嘌呤核苷二磷酸的总量减少，但从原肠胚到神经胚则急剧增加。ADP的水平遵循这一模式，但GDP的水平在这三个阶段没有显著变化。受精后立即增加的嘌呤核苷三磷酸水平，在桑椹胚、原肠胚和神经胚阶段几乎保持恒定。与嘌呤核苷二磷酸一样，腺嘌呤核苷酸从桑椹胚到原肠胚减少，从原肠胚到神经胚增加。相比之下，GTP的水平在原肠胚阶段出现急剧峰值。从桑椹胚到神经胚，嘧啶核苷三磷酸的总量没有显著变化。与发育的先前阶段一样，仅检测到尿苷糖核苷酸。在原肠胚阶段发现核苷酸的半乳糖基酯急剧增加。
