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阿根廷蟾蜍肝脏中嘌呤碱、核苷酸和核苷酸糖的浓度及季节变化。与早期胚胎发育的比较。

Concentration and seasonal variations of purine bases, nucleotides and nucleotide-sugars in liver of Bufo arenarum. Comparison with early embryogenesis.

作者信息

Maggese M C, Spaizmann R C, de Recondo M E

出版信息

Acta Physiol Lat Am. 1976;26(6):472-80.

PMID:829917
Abstract

A comparative study of the bases, nucleotides and nucleotide-sugars was performed in liver of Bufo arenarum. Samples were obtained at different seasons of the year, according to the periods of active (December-March) and passive metabolism (April-July). It was found that guanine and hypoxanthine increase significantly in spring. A remarkable decrease in the levels of the nucleosides triphosphates adenosine 5'-triphosphate (ATP) and guanosine 5'-triphosphate (GTP) was found in spring; correlatively, an increase in the levels of adenosine 5'-monophosphate (AMP) and guanosine 5'-monophosphate (GMP) and adenosine 5'-pyrophosphate (ADP) and guanosine 5'-pyrophosphate (GDP was observed. A notable increase in the amounts of uridine 5'-diphosphate- D - glucose (UDP-glucose) was detected at the end of the period of low metabolism, which is coincident wtih a decrease in the level of glycogen, observed by other authors.

摘要

对阿根廷蟾蜍肝脏中的碱基、核苷酸和核苷酸糖进行了一项比较研究。根据活跃代谢期(12月至3月)和被动代谢期(4月至7月),在一年中的不同季节采集样本。研究发现,春季鸟嘌呤和次黄嘌呤显著增加。春季发现三磷酸腺苷(ATP)和三磷酸鸟苷(GTP)的核苷三磷酸水平显著下降;相应地,观察到一磷酸腺苷(AMP)、一磷酸鸟苷(GMP)、二磷酸腺苷(ADP)和二磷酸鸟苷(GDP)水平升高。在低代谢期结束时检测到尿苷5'-二磷酸-D-葡萄糖(UDP-葡萄糖)的量显著增加,这与其他作者观察到的糖原水平下降相一致。

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