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The penetration of dirithromycin into bronchoalveolar lavage fluid and alveolar macrophages.地红霉素在支气管肺泡灌洗液和肺泡巨噬细胞中的渗透情况。
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Smoking-induced changes in epithelial lining fluid volume, cell density and protein.吸烟引起的上皮衬液体积、细胞密度和蛋白质的变化。
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Streptococcus pneumoniae bacteraemia: pharmacodynamic correlations with outcome and macrolide resistance--a controlled study.肺炎链球菌菌血症：与转归及大环内酯类耐药性的药效学相关性——一项对照研究
Int J Antimicrob Agents. 2007 Sep;30(3):264-9. doi: 10.1016/j.ijantimicag.2007.04.013. Epub 2007 Jun 22.
2
Pharmacokinetics of gatifloxacin after a single oral dose in healthy young adult subjects and adult patients with chronic bronchitis, with a comparison of drug concentrations obtained by bronchoscopic microsampling and bronchoalveolar lavage.加替沙星在健康年轻成人受试者和成年慢性支气管炎患者单次口服给药后的药代动力学，以及通过支气管镜微量采样和支气管肺泡灌洗获得的药物浓度比较。
Clin Ther. 2007 Jan;29(1):123-30. doi: 10.1016/j.clinthera.2007.01.005.
3
Pharmacokinetics of telithromycin using bronchoscopic microsampling after single and multiple oral doses.单次和多次口服后使用支气管镜微量取样法测定泰利霉素的药代动力学
Pulm Pharmacol Ther. 2007;20(5):549-55. doi: 10.1016/j.pupt.2006.05.006. Epub 2006 Jun 12.
4
Pharmacokinetic considerations in the treatment of CNS tumours.中枢神经系统肿瘤治疗中的药代动力学考量
Clin Pharmacokinet. 2006;45(9):871-903. doi: 10.2165/00003088-200645090-00002.
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Blood-neural barrier: intercellular communication at glio-vascular interface.血-神经屏障：神经胶质-血管界面处的细胞间通讯
J Biochem Mol Biol. 2006 Jul 31;39(4):339-45. doi: 10.5483/bmbrep.2006.39.4.339.
6
Intrapulmonary pharmacokinetics and pharmacodynamics of high-dose levofloxacin in healthy volunteer subjects.健康志愿者中高剂量左氧氟沙星的肺内药代动力学和药效学
Int J Antimicrob Agents. 2006 Aug;28(2):114-21. doi: 10.1016/j.ijantimicag.2006.03.022. Epub 2006 Jul 11.
7
Delivering drugs to the central nervous system: a medicinal chemistry or a pharmaceutical technology issue?将药物递送至中枢神经系统：是药物化学问题还是制药技术问题？
Curr Med Chem. 2006;13(15):1757-75. doi: 10.2174/092986706777452461.
8
Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery.药物代谢与药代动力学、血脑屏障及中枢神经系统药物发现
NeuroRx. 2005 Oct;2(4):554-71. doi: 10.1602/neurorx.2.4.554.
9
Drug delivery across the blood-brain barrier.药物透过血脑屏障的递送
Curr Drug Deliv. 2004 Oct;1(4):361-76. doi: 10.2174/1567201043334542.
10
Intrapulmonary pharmacokinetics and pharmacodynamics of meropenem.美罗培南的肺内药代动力学和药效学
Int J Antimicrob Agents. 2005 Dec;26(6):449-56. doi: 10.1016/j.ijantimicag.2005.08.015. Epub 2005 Nov 8.

Interpretation of antibiotic concentration ratios measured in epithelial lining fluid.

作者信息

Kiem Sungmin, Schentag Jerome J

机构信息

University at Buffalo School of Pharmaceutical Sciences and Pharmacy, Hochstetter Hall 445, Buffalo, NY 14260, USA.

出版信息

Antimicrob Agents Chemother. 2008 Jan;52(1):24-36. doi: 10.1128/AAC.00133-06. Epub 2007 Sep 10.

DOI:10.1128/AAC.00133-06
PMID:17846133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2223903/
Abstract
摘要