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在抗高血压和降脂治疗预防心脏病发作试验中西班牙裔人群的血压控制情况

Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.

作者信息

Margolis Karen L, Piller Linda B, Ford Charles E, Henriquez Mario A, Cushman William C, Einhorn Paula T, Colon Pedro J, Vidt Donald G, Christian Rudell, Wong Nathan D, Wright Jackson T, Goff David C

机构信息

HealthPartners Research Foundation PO Box 1524, Mailstop 21111R, Minneapolis, MN 55440-1524, USA.

出版信息

Hypertension. 2007 Nov;50(5):854-61. doi: 10.1161/HYPERTENSIONAHA.107.092650. Epub 2007 Sep 10.

DOI:10.1161/HYPERTENSIONAHA.107.092650
PMID:17846352
Abstract

Historically, blood pressure control in Hispanics has been considerably less than that of non-Hispanic whites and blacks. We compared determinants of blood pressure control among Hispanic white, Hispanic black, non-Hispanic white, and non-Hispanic black participants (N=32 642) during follow-up in a randomized, practice-based, active-controlled trial. Hispanic blacks and whites represented 3% and 16% of the cohort, respectively; 33% were non-Hispanic black and 48% were non-Hispanic white. Hispanics were less likely to be controlled (<140/90 mm Hg) at enrollment, but within 6 to 12 months of follow-up, Hispanics had a greater proportion <140/90 mm Hg compared with non-Hispanics. At 4 years of follow-up, blood pressure was controlled in 72% of Hispanic whites, 69% of Hispanic blacks, 67% of non-Hispanic whites, and 59% of non-Hispanic blacks. Compared with non-Hispanic whites, Hispanic whites had a 20% greater odds of achieving BP control by 2 years of follow-up (odds ratio: 1.20; 95% CI: 1.10 to 1.31) after controlling for demographic variables and comorbidities, Hispanic blacks had a similar odds of achieving BP control (odds ratio: 1.04; 95% CI: 0.86 to 1.25), and non-Hispanic blacks had a 27% lower odds (odds ratio: 0.73; 95% CI: 0.69 to 0.78). We conclude that in all patients high levels of blood pressure control can be achieved with commonly available medications and that Hispanic ethnicity is not associated with inferior control in the setting of a clinical trial in which hypertensive patients had equal access to medical care, and medication was provided at no cost.

摘要

从历史上看,西班牙裔人群的血压控制情况一直远低于非西班牙裔白人和黑人。在一项基于实践的随机、活性对照试验的随访过程中,我们比较了西班牙裔白人、西班牙裔黑人、非西班牙裔白人和非西班牙裔黑人参与者(N = 32642)血压控制的决定因素。西班牙裔黑人和白人分别占队列的3%和16%;33%为非西班牙裔黑人,48%为非西班牙裔白人。西班牙裔在入组时血压得到控制(<140/90 mmHg)的可能性较小,但在随访6至12个月内,与非西班牙裔相比,血压<140/90 mmHg的西班牙裔比例更高。在随访4年时,72%的西班牙裔白人、69%的西班牙裔黑人、67%的非西班牙裔白人和59%的非西班牙裔黑人血压得到控制。与非西班牙裔白人相比,在控制了人口统计学变量和合并症后,西班牙裔白人在随访2年时实现血压控制的几率高20%(优势比:1.20;95%置信区间:1.10至1.31),西班牙裔黑人实现血压控制的几率相似(优势比:1.04;95%置信区间:

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