肌酐和胱抑素C的个体内变异
Intra-individual variation in creatinine and cystatin C.
作者信息
Bandaranayake Niluka, Ankrah-Tetteh Thelma, Wijeratne Sethsiri, Swaminathan Ramasamyiyer
机构信息
Department of Chemical Pathology, St. Thomas' Hospital, London, UK.
出版信息
Clin Chem Lab Med. 2007;45(9):1237-9. doi: 10.1515/CCLM.2007.256.
BACKGROUND
Serum creatinine and cystatin C are measured in the assessment of glomerular filtration rate. Biological variation of an analyte is an important determinant of its usefulness. Intra-individual variation in serum creatinine and cystatin C in healthy subjects was determined in this study.
METHODS
Weekly blood samples were taken from 10 healthy subjects and analysed for creatinine (kinetic Jaffe method) and for cystatin C (by nephelometry).
RESULTS
Intra-individual variations for serum creatinine and cystatin C were 6.1% and 4.55%, respectively. Index of individuality values were similar for the analytes (0.35 for both).
CONCLUSION
Intra-individual variations for serum creatinine and cystatin C were similar in healthy subjects.
背景
血清肌酐和胱抑素C用于评估肾小球滤过率。分析物的生物学变异是其有用性的重要决定因素。本研究测定了健康受试者血清肌酐和胱抑素C的个体内变异。
方法
从10名健康受试者每周采集血样，分析肌酐（动力学Jaffe法）和胱抑素C（比浊法）。
结果
血清肌酐和胱抑素C的个体内变异分别为6.1%和4.55%。两种分析物的个体性指数值相似（均为0.35）。
结论
健康受试者血清肌酐和胱抑素C的个体内变异相似。
Zotero 插件