与多发性硬化症患者相比，缺血性中风年轻患者的生活质量。
Quality of life among young patients with ischaemic stroke compared with patients with multiple sclerosis.
作者信息
Naess H, Beiske A G, Myhr K-M
机构信息
Department of Neurology, Haukeland University Hospital, University of Bergen, Bergen, Norway.
出版信息
Acta Neurol Scand. 2008 Mar;117(3):181-5. doi: 10.1111/j.1600-0404.2007.00923.x. Epub 2007 Sep 11.
OBJECTIVES
We aimed to evaluate the quality of life among young ischaemic stroke (IS) patients at long-term follow-up by comparing them with multiple sclerosis (MS) patients with secondary progressive course. The mean age at stroke onset was 41.6 years.
METHODS
Nottingham Health Profile scores were obtained from 191 IS patients 6 years (mean) after the index stroke, from 337 MS patients 5 years (mean) after the onset of the secondary progressive course and from 216 controls.
RESULTS
The mean age of IS patients was 47.8 years and MS patients 44.5 years at follow-up. The MS patients as a group had worse subscores than the IS patients. When adjusting for physical mobility, complaints of fatigue (P = 0.012) were more frequent among MS patients, whereas pain (P < 0.001) and sleep (P = 0.007) disturbances were more frequent among IS patients.
CONCLUSION
The comparison of IS and MS patients highlights the importance of pain and sleep disturbances among IS patients when adjusting for physical mobility.
目的
我们旨在通过将年轻缺血性卒中（IS）患者与继发进展型多发性硬化（MS）患者进行比较，评估其长期随访中的生活质量。卒中发病的平均年龄为41.6岁。
方法
从191例IS患者（卒中发病后平均6年）、337例MS患者（继发进展病程开始后平均5年）和216例对照中获取诺丁汉健康量表评分。
结果
随访时IS患者的平均年龄为47.8岁，MS患者为44.5岁。MS患者组的各项子评分比IS患者差。在调整身体活动能力后，MS患者中疲劳主诉（P = 0.012）更常见，而IS患者中疼痛（P < 0.001）和睡眠障碍（P = 0.007）更常见。
结论
IS患者与MS患者的比较突出了在调整身体活动能力时，IS患者中疼痛和睡眠障碍的重要性。
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