Department of Kinesiology and Community Health, University of Illinois, 233 Freer Hall, Urbana, IL 61801, USA.
Qual Life Res. 2013 Mar;22(2):253-61. doi: 10.1007/s11136-012-0149-z. Epub 2012 Mar 9.
Physical activity and self-efficacy represent behavioral and psychological factors, respectively, that are compromised in persons with multiple sclerosis (MS), but might be modifiable through intervention and result in better health-related quality of life (HRQOL).
The present study adopted a panel research design and examined the associations between individual-level changes in physical activity, self-efficacy, and HRQOL over a one-year period in persons with MS.
The sample consisted of 269 persons with relapsing-remitting MS who completed the Godin Leisure-Time Questionnaire (GLTEQ), Multiple Sclerosis Self-Efficacy (MSSE) Scale, and Multiple Sclerosis Quality of Life-29 (MSIS-29) Scale on two occasions that were separated by 1 year. The data were analyzed using panel analysis in Mplus 3.0.
The initial panel analysis indicated that individual-level change in physical activity was associated with individual-level change in both physical and psychological HRQOL. The subsequent panel analysis indicated that (a) individual-level change in self-efficacy for functioning with MS was associated with individual-level change in physical HRQOL, whereas individual-level change in self-efficacy for control was associated with individual-level change in psychological HRQOL; (b) individual-level change in self-efficacy for functioning with MS, but not self-efficacy for control, mediated the association between individual-level change in physical activity and physical HRQOL; and (c) individual-level change in self-efficacy for controlling MS was the strongest predictor of individual-level change in HRQOL.
Physical activity and self-efficacy both might be important targets of subsequent behavioral and self-management interventions for improving the HRQOL of persons with MS, although self-efficacy is seemingly more important than physical activity.
体力活动和自我效能感分别代表行为和心理因素，在多发性硬化症（MS）患者中受到损害，但可以通过干预进行改变，并导致更好的健康相关生活质量（HRQOL）。
本研究采用面板研究设计，在 1 年内检查了多发性硬化症患者的体力活动、自我效能感和 HRQOL 的个体水平变化之间的关联。
该样本由 269 名复发性缓解型多发性硬化症患者组成，他们在 1 年内完成了 Godin 休闲时间问卷（GLTEQ）、多发性硬化症自我效能感（MSSE）量表和多发性硬化症生活质量-29 量表（MSIS-29）两次。使用 Mplus 3.0 中的面板分析对数据进行分析。
初始面板分析表明，体力活动的个体水平变化与身体和心理 HRQOL 的个体水平变化均相关。随后的面板分析表明：（a）MS 功能自我效能的个体水平变化与身体 HRQOL 的个体水平变化相关，而控制自我效能的个体水平变化与心理 HRQOL 的个体水平变化相关；（b）MS 功能自我效能的个体水平变化，但不是控制自我效能，介导了体力活动个体水平变化与身体 HRQOL 之间的关联；（c）控制 MS 的自我效能的个体水平变化是 HRQOL 个体水平变化的最强预测因子。
体力活动和自我效能感可能都是改善多发性硬化症患者 HRQOL 的后续行为和自我管理干预的重要目标，尽管自我效能感似乎比体力活动更重要。
