Tang Bo, Liu Xia, Xu Kehua, Huang Hui, Yang Guiwen, An Liguo
College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Shandong Normal University, Jinan 250014, P. R. China.
Chem Commun (Camb). 2007 Sep 28(36):3726-8. doi: 10.1039/b707173f. Epub 2007 Jul 9.
A dual near-infrared pH fluorescent probe has been designed, synthesized and applied to HepG2 cells, with a pK(a) value of 5.14 under acidic conditions and 11.31 under basic conditions, which is valuable for studying acidic organelles in living cells and pH changes in chemical systems.
一种双近红外pH荧光探针已被设计、合成并应用于HepG2细胞，其在酸性条件下的pK(a)值为5.14，在碱性条件下为11.31，这对于研究活细胞中的酸性细胞器和化学系统中的pH变化具有重要价值。
