Duff Kevin, Schoenberg Mike R, Mold James W, Scott James G, Adams Russell L
Department of Psychiatry, University of Iowa, Iowa City, IA 52242-1000, USA.
J Clin Exp Neuropsychol. 2007 Nov;29(8):854-9. doi: 10.1080/13803390601147629. Epub 2007 Feb 19.
Several neuropsychological disorders have been classified as having either "cortical" or "subcortical" profiles; however, little information is available about the frequency of these profiles in the normal population or their stability on retesting. Therefore, the current study calculated the cortical/subcortical profile index from the Repeatable Battery for the Assessment of Neuropsychological Status in a large cohort (n = 793) of older adult primary care patients. The frequency of these profiles was examined, as was their stability across 1- and 2-year periods. Cortical profiles were quite common in this sample, with 37% having 10 or more points on this index. Stability of these index scores across 1 and 2 years was moderate (r = .58-.61). Although the utility of this index needs to be investigated in clinical samples, practitioners should use caution when interpreting these types of indicator as pathognomonic for the presence of disease.
几种神经心理障碍已被归类为具有“皮质型”或“皮质下型”特征；然而，关于这些特征在正常人群中的出现频率或复测时的稳定性，几乎没有相关信息。因此，本研究在一大群（n = 793）老年初级保健患者中，根据可重复神经心理状态评估量表计算皮质/皮质下特征指数。研究了这些特征的出现频率以及它们在1年和2年期间的稳定性。皮质型特征在该样本中相当常见，37%的人在该指数上得分达到10分或更高。这些指数得分在1年和2年期间的稳定性中等（r = 0.58 - 0.61）。尽管该指数的效用需要在临床样本中进行研究，但从业者在将这类指标解释为疾病存在的确诊依据时应谨慎。
