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用于评估神经心理状态的可重复性成套测验(RBANS):初步临床效度

The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): preliminary clinical validity.

作者信息

Randolph C, Tierney M C, Mohr E, Chase T N

机构信息

Department of Neurology, Loyola University Medical Center, Maywood, IL, USA.

出版信息

J Clin Exp Neuropsychol. 1998 Jun;20(3):310-9. doi: 10.1076/jcen.20.3.310.823.

DOI:10.1076/jcen.20.3.310.823
PMID:9845158
Abstract

Neuropsychological assessment of older individuals with dementing illnesses has suffered from a lack of appropriately designed test instruments. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) was developed for the dual purposes of identifying and characterizing abnormal cognitive decline in the older adult and as a neuropsychological screening battery for younger patients. The entire battery takes less than 30 minutes to administer, and yields scaled scores for five cognitive domains. The current study reports preliminary clinical validity results with the RBANS, comparing very mildly demented patients with a diagnosis of probable Alzheimer's disease (n = 20) to patients with Huntington's disease (n = 20) and normal controls (n = 40). Although the patient groups had essentially identical total scores on the RBANS, they exhibited opposite profiles, differing significantly on four of the five subsections. The AD patients performed most poorly on Language, and Delayed Memory subsections, while the HD patients obtained their lowest scaled scores on the Attention and the Visuospatial/Constructional subsections. These results are consistent with the neuropsychological profiles of these dementing disorders derived from lengthier standardized tests and experimental investigations. In addition, even those patients who performed above the suggested cut-off points on the MMSE and the Dementia Rating Scale scored significantly below their controls on the RBANS. These data suggest that the RBANS is effective at both detecting and characterizing dementia of different etiologies.

摘要

对患有痴呆症的老年人进行神经心理学评估一直受到缺乏适当设计的测试工具的困扰。可重复神经心理状态评估量表(RBANS)的开发有两个目的:一是识别和描述老年人异常的认知衰退,二是作为针对年轻患者的神经心理学筛查量表。完成整个量表的测试用时不到30分钟,并能得出五个认知领域的量表分数。本研究报告了RBANS的初步临床效度结果,将20名诊断为可能患有阿尔茨海默病的极轻度痴呆患者与20名亨廷顿病患者及40名正常对照进行了比较。尽管各患者组在RBANS上的总分基本相同,但他们呈现出相反的概况,在五个子部分中的四个上存在显著差异。阿尔茨海默病患者在语言和延迟记忆子部分表现最差,而亨廷顿病患者在注意力和视觉空间/结构子部分获得的量表分数最低。这些结果与通过更长时间的标准化测试和实验研究所得出的这些痴呆症的神经心理学概况一致。此外,即使那些在简易精神状态检查表(MMSE)和痴呆评定量表上得分高于建议临界点的患者,在RBANS上的得分也显著低于其对照组。这些数据表明,RBANS在检测和描述不同病因的痴呆症方面均有效。

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