Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China.
Fitoterapia. 2012 Apr;83(3):563-7. doi: 10.1016/j.fitote.2011.12.027. Epub 2012 Jan 8.
A new lignan glucoside, (+)-(7S,8R,8'R)-lyoniresinol 9-O-β-D-(6″-O-trans-sinapoyl)glucopyranoside (1), and a new iridoid glucoside, 10-O-trans-sinapoylgeniposide (2), together with eight known compounds, were isolated from the fruits of Gardenia jasminoides Ellis. The structures of the isolates were elucidated by extensive spectroscopic studies, including UV, IR, 1D and 2D NMR, ESI-MS, HR-ESI-MS, and CD experiments. The short-term-memory-enhancement activities of some compounds were evaluated on an Aβ transgenic drosophila model.
从栀子（Gardenia jasminoides Ellis）果实中分离得到了两个新的木脂素葡萄糖苷（(+)-(7S,8R,8'R)-lyoniresinol 9-O-β-D-(6″-O-反式-芥子酰基)吡喃葡萄糖苷（1）和 10-O-反式-芥子酰基京尼平苷（2））和八个已知化合物。通过广泛的光谱研究，包括 UV、IR、1D 和 2D NMR、ESI-MS、HR-ESI-MS 和 CD 实验，确定了这些分离物的结构。在 Aβ 转基因果蝇模型上评价了一些化合物的短期记忆增强活性。
