Tekdogan Umit, Tuncel Altug, Nalcacioglu Varol, Kisa Cebrail, Aslan Yilmaz, Atan Ali
Third Department of Urology, Ankara Numune Research and Training Hospital, Ministry of Health, Sihhiye, Ankara, Turkey.
Scand J Urol Nephrol. 2008;42(1):24-8. doi: 10.1080/00365590701514555. Epub 2007 Jul 27.
To investigate the effect of anxiety on the pain level of patients during transrectal prostate needle biopsy.
A total of 160 consecutive patients underwent prostate biopsy. Group 1 consisted of 86 patients who received bilateral periprostatic infiltration of 5 cm(3) of 2% lidocaine. Group 2 included 74 patients and they received bilateral periprostatic infiltration of 5 cm(3) of 0.9% saline solution. The Stait-Trait Anxiety Inventory was administered before the biopsy. The patients' mean pain scores were assessed by means of a visual analog scale (VAS) during digital rectal examination, probe insertion and biopsy.
The mean age of the patients was 67.8 years (range 46-79 years). When the two groups were compared regarding the level of pain during DRE and probe insertion, no significant differences were found. The mean VAS score for biopsy was significantly lower in Group 1. In Group 1, the mean VAS scores were similar in patients with no and moderate trait anxiety levels. However, the mean VAS score was significantly higher in patients who had severe trait anxiety than in the others (p=0.002). In Group 2, the differences in VAS scores reached statistical significance between no and moderate, no and severe, and moderate and severe trait anxiety levels (p=0.001). When the state anxiety levels were considered, the mean VAS scores were significantly higher in patients with severe state anxiety scores in Groups 1 and 2 (p=0.003 and 0.001, respectively).
We found a significant relationship between trait and state anxiety levels and pain scores in patients who underwent transrectal prostate needle biopsy.
探讨焦虑对经直肠前列腺穿刺活检患者疼痛程度的影响。
共有160例连续患者接受前列腺活检。第1组由86例患者组成，他们接受了双侧前列腺周围5 cm³的2%利多卡因浸润。第2组包括74例患者，他们接受了双侧前列腺周围5 cm³的0.9%盐溶液浸润。在活检前使用状态-特质焦虑量表进行评估。在直肠指检、探头插入和活检过程中，通过视觉模拟量表（VAS）评估患者的平均疼痛评分。
患者的平均年龄为67.8岁（范围46 - 79岁）。比较两组在直肠指检和探头插入时的疼痛程度，未发现显著差异。第1组活检的平均VAS评分显著较低。在第1组中，无特质焦虑和中度特质焦虑水平的患者平均VAS评分相似。然而，具有严重特质焦虑的患者的平均VAS评分显著高于其他患者（p = 0.002）。在第2组中，无、中度、无、重度以及中度和重度特质焦虑水平之间的VAS评分差异具有统计学意义（p = 0.001）。当考虑状态焦虑水平时，第1组和第2组中具有严重状态焦虑评分的患者的平均VAS评分显著更高（分别为p = 0.003和0.001）。
我们发现经直肠前列腺穿刺活检患者的特质和状态焦虑水平与疼痛评分之间存在显著关系。
