Farkas M, Tárczy C, Tóth E
Markhot Ferenc Kórház-Rendelöintézet, Szülészet-Nögyógyászati Osztály, Eger.
Acta Pharm Hung. 1991 Sep;61(5):262-76.
Authors used the tablet Bromocriptine in 22 cases for the treatment of infertility and in 15 cases for that of extra-puerperal galactorrhoea. The serum-prolactin level of the patients of the two groups remained in 16 cases below and in 13 cases beyond of the upper value of the normal menstrual cycle. It turned out, that the average prolactin-level of patients, treated against infertility, diminished significantly even after one month after the treatment. Between the values of serum FSH, before and after LH treatment there have not been found any significant difference. On the contrary, in the values of serum progesterone and 17-beta-oestradiol significant differences have been observed after treatments of one month as well as of two months duration. On the basis of the results, authors can state, that the prevailing progesterone-level is the adequate indicator of potential fertility. During the treatment of hyperprolactinaemic pathologies eight pregnancies occurred (21.6%). It turned out, that hyperprolactinaemia was the real cause of procured abortion. For the registration of latent hyperprolactinaemia the Cerucal (metoclopramide) load proved to be an adequate diagnostical method.
作者使用溴隐亭片剂治疗22例不孕症患者和15例非产褥期溢乳患者。两组患者的血清催乳素水平，16例保持在正常月经周期上限值以下，13例超过该值。结果显示，治疗不孕症的患者，即使在治疗后一个月，其平均催乳素水平也显著降低。促黄体生成素（LH）治疗前后，血清促卵泡生成素（FSH）值未发现任何显著差异。相反，治疗一个月及两个月后，血清孕酮和17-β-雌二醇值出现了显著差异。根据这些结果，作者可以指出，主要的孕酮水平是潜在生育能力的适当指标。在高催乳素血症相关病症的治疗过程中，发生了8例妊娠（21.6%）。结果表明，高催乳素血症是习惯性流产的真正原因。对于隐匿性高催乳素血症的诊断，胃复安（甲氧氯普胺）负荷试验被证明是一种合适的诊断方法。
