Rao You-Sheng, Wang Zhang-Feng, Zhou Min, Shen Xu, Xia Meng-Na, Zhang Xi-Quan
College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
Yi Chuan. 2007 Sep;29(9):1083-8. doi: 10.1360/yc-007-1083.
A region (200 kb) of Contig. 060226.1 on GGA1 was selected to study the average diversity of Red Jungle Fowl (RJF), Taihe Silk chicken (TS), and White Recessive Rock (WRR), and estimate the effective population size (Ne) of chicken. The mean heterozygosities of RJF, TS and WRR were 0.28533+/-0.034747, 0.32926+/-0.039191 and 0.30168+/-0.040382, respectively. Significant test indicted that there is not significant difference between them (P=0.2368>0.05). The initial chicken effective population size was estimated to be about 20 000-150 000. Chicken has undergone serious population bottleneck effect during the first stage of domestication. However, this bottleneck effect did not result in a substantial loss of diversity as revealed by SNP. The possible explanations for similar SNP diversity between domesticated chicken and Red Jungle Fowl might due to many factors, such as a big Ne in earlier phase of domestication, population expending in breed differentiation, abroad crossing between breeds (especially crossing with RJF), together with high recombination rate in chicken genome.
选择GGA1上Contig. 060226.1的一个区域（200 kb）来研究原鸡、泰和丝羽乌骨鸡和白洛克鸡的平均多样性，并估计鸡的有效种群大小（Ne）。原鸡、泰和丝羽乌骨鸡和白洛克鸡的平均杂合度分别为0.28533±0.034747、0.32926±0.039191和0.30168±0.040382。显著性检验表明它们之间没有显著差异（P = 0.2368>0.05）。鸡的初始有效种群大小估计约为20000 - 150000。在驯化的第一阶段，鸡经历了严重的种群瓶颈效应。然而，如SNP所揭示的，这种瓶颈效应并没有导致多样性的大量丧失。驯化鸡和原鸡之间SNP多样性相似的可能解释可能有许多因素，如驯化早期较大的有效种群大小、品种分化过程中的种群扩张、品种间的广泛杂交（特别是与原鸡杂交），以及鸡基因组中的高重组率。
