Beich Anders, Gannik Dorte, Saelan Henrik, Thorsen Thorkil
Research Unit and Department for General Practice, University of Copenhagen, Centre for Health and Community, Oster Farimagsgade 5, DK-1014 Copenhagen K, Denmark.
Alcohol Alcohol. 2007 Nov-Dec;42(6):593-603. doi: 10.1093/alcalc/agm063. Epub 2007 Sep 11.
Recommendations for routine alcohol screening and brief counselling intervention in primary health care rest on results from intervention efficacy studies. By conducting a pragmatic controlled trial (PCT), we aimed at evaluating the effectiveness of the WHO recommendations for screening and brief intervention (SBI) in general practice.
A randomized PCT (brief counselling intervention vs no intervention) involving 39 Danish general practitioners (GPs). Systematic screening of 6897 adults led to inclusion of 906 risky drinkers, and research follow-up on 537 of these after 12-14 months. Outcome measures focused on patients' acceptance of screening and intervention and their self-reported alcohol consumption.
Patient acceptance of screening and intervention -10.3% (N = 794) of the target population (N = 7, 691) explicitly refused screening. All intervention group subjects (N = 442) were exposed to an instant brief counselling session while only 17.9% of them (79/442) attended a follow-up consultation that was offered by their GP. Consumption Changes At one-year follow-up, average weekly consumption had increased by 0.7 drinks in both comparison groups. As secondary findings, we observed an indiscriminate absolute risk reduction (ARR = 0.08 (95% CI: -0.02; 0.18)) in male binge drinking, but adverse intervention effects for women on the secondary outcomes (binge drinking ARR = -0.30 (95% CI: -0.47; -0.09)).
The results of brief interventions in everyday general practice performed on the basis of systematic questionnaire screening may fall short of theoretical expectations. When applied to non-selected groups in everyday general practice SBI may have little effect and engender diverse outcome. Women may be more susceptible to defensive reactions than men.
初级卫生保健中常规酒精筛查及简短咨询干预的建议基于干预效果研究的结果。通过开展一项实用性对照试验(PCT),我们旨在评估世界卫生组织关于在全科医疗中进行筛查及简短干预(SBI)建议的有效性。
一项随机PCT(简短咨询干预组与无干预组),涉及39名丹麦全科医生(GP)。对6897名成年人进行系统筛查,共纳入906名危险饮酒者,并在12 - 14个月后对其中537人进行研究随访。结局指标聚焦于患者对筛查及干预的接受度以及他们自我报告的酒精消费量。
患者对筛查及干预的接受度 - 目标人群(N = 7691)中有10.3%(N = 794)明确拒绝筛查。所有干预组受试者(N = 442)都接受了即时简短咨询,然而其中只有17.9%(79/442)参加了由其全科医生提供的随访咨询。消费量变化 - 在一年随访时,两个比较组的平均每周饮酒量均增加了0.7杯。作为次要发现,我们观察到男性暴饮的绝对风险有非特异性降低(ARR = 0.08(95%CI: - 0.02;0.18)),但干预对女性的次要结局有不良影响(暴饮ARR = - 0.30(95%CI: - 0.47; - 0.09))。
基于系统问卷筛查在日常全科医疗中进行简短干预的结果可能未达理论预期。当应用于日常全科医疗中的非特定人群时,SBI可能效果甚微且会产生不同结果。女性可能比男性更容易出现防御性反应。