癌症患者中的抗核抗体及抗爱泼斯坦-巴尔病毒滴度升高
Antinuclear antibodies and elevated anti-Epstein-Barr virus titers in cancer patients.
作者信息
McCormick N K, McCormick K J, Trentin J J
出版信息
Infect Immun. 1976 May;13(5):1382-6. doi: 10.1128/iai.13.5.1382-1386.1976.
Abstract
One and one-half percent of human sera from patients seen at a clinic for treatment of cancer contained antibodies to the nuclei of chick kidney cells by indirect immunofluorescence tests. In the group of sera containing antinuclear antibodies, the geometric mean titer to Epstein-Barr virus (EBV) capsid antigen was significantly elevated. Sera obtained from normal adults or from patients with similar histological types of tumors that possessed no antinuclear antibodies contained lower levels of anti-EBV antibodies. The elevated titers to EBV were correlated with the presence or absence of antinuclear antibodies and not with a particular type or site of neoplastic disease.
摘要
通过间接免疫荧光试验发现，在一家癌症治疗诊所就诊的患者中，1.5%的人血清含有针对鸡肾细胞核的抗体。在含有抗核抗体的血清组中，针对爱泼斯坦-巴尔病毒（EBV）衣壳抗原的几何平均滴度显著升高。从正常成年人或患有无抗核抗体的相似组织学类型肿瘤的患者中获得的血清，其抗EBV抗体水平较低。EBV滴度升高与抗核抗体的存在与否相关，而与肿瘤疾病的特定类型或部位无关。
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The development of chick-embryo-lethal-orphan (CELO) virus T and V antigens in lytically infected chick kidney cells.
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