Frydrychowski Andrzej F, Pluciński Jerzy
Medical University of Gdańsk, Department of Physiology, ul. Debinki 1, 80-211 Gdańsk, Poland.
J Biomed Opt. 2007 Jul-Aug;12(4):044016. doi: 10.1117/1.2753756.
The study presents comparison of near-infrared light propagation and near-infrared backscattered radiation power, as simulated with numerical modeling and measured live in a patient in clinical conditions with the use of the near-infrared transillumination-backscattering sounding (NIR-TBSS) technique. A unique chance for such precise comparative analysis was available to us in a clinical case of a female patient with scalp removed from one half of the head due to injury. The analysis performed indicates that the difference between the intensity of the signals in numerical modeling and live measurements is less than 4 dB. Analysis of the theoretical model also provides hints on the positioning of the two detectors relative to the source of radiation. Correctness of these predicted values is confirmed in practical application, when changes of signals received by the detectors are recorded, along with changes of the width of the subarachnoid space. What is more, the power distribution of the spectrum of near-infrared backscattered radiation returning to the detectors is confirmed in the real recording in the patient. An abridged description of the new method of NIR-TBSS is presented.
该研究展示了近红外光传播与近红外背向散射辐射功率的比较，这是通过数值模拟以及在临床条件下对一名患者进行活体测量得到的，测量采用近红外透照 - 背向散射探测（NIR - TBSS）技术。在一名因受伤导致头部一侧头皮被切除的女性患者的临床病例中，我们获得了进行这种精确对比分析的独特机会。所进行的分析表明，数值模拟信号强度与活体测量信号强度之间的差异小于4分贝。对理论模型的分析还为两个探测器相对于辐射源的定位提供了线索。当记录探测器接收到的信号变化以及蛛网膜下腔宽度变化时，这些预测值在实际应用中得到了证实。此外，患者实际记录中也证实了返回探测器的近红外背向散射辐射光谱的功率分布。文中还简要介绍了NIR - TBSS新方法。
