Department of Radiology Informatics and Statistics, Medical University of Gdansk, Tuwima Str. 15, 80-210, Gdansk, Poland.
Department of Biomedical Engineering, Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, Gdansk, Poland.
Sci Rep. 2020 Oct 29;10(1):18668. doi: 10.1038/s41598-020-75037-1.
The aim of the study was to compare simultaneously recorded a NIR-T/BSS and NIRS signals from healthy volunteers. NIR-T/BSS is a device which give an ability to non-invasively detect and monitor changes in the subarachnoid space width (SAS). Experiments were performed on a group of 30 healthy volunteers (28 males and 2 females, age 30.8 ± 13.4 years, BMI = 24.5 ± 2.3 kg/m). We analysed recorded signals using analysis methods based on wavelet transform (WT) for the wide frequency range from 0.0095 to 2 Hz. Despite the fact that both devices use a similar radiation source both signals are distinct from each other. We found statistically significant differences for WT amplitude spectra between both signals. Additionally, we showed different relationships of both signals to blood pressure. Collectively, based on the present findings and those of previous studies, we can conclude that the combination of NIR-T/BSS or NIRS signals and time-frequency analysis opens new frontiers in science, and give possibility to understand and diagnosis of various neurodegenerative and ageing related diseases to improve diagnostic procedures and patient prognosis.
本研究旨在比较健康志愿者同时记录的近红外光谱经颅/脑池（T/BSS）和近红外光谱（NIRS）信号。NIR-T/BSS 是一种能够非侵入性地检测和监测蛛网膜下腔宽度（SAS）变化的设备。该实验在一组 30 名健康志愿者（28 名男性和 2 名女性，年龄 30.8±13.4 岁，BMI=24.5±2.3kg/m²）中进行。我们使用基于小波变换（WT）的分析方法对从 0.0095 到 2Hz 的宽频率范围进行了记录信号的分析。尽管两种设备使用类似的辐射源，但两种信号彼此不同。我们发现两种信号的 WT 振幅谱之间存在统计学上的显著差异。此外，我们还显示了两种信号与血压的不同关系。综上所述，基于目前的发现和以前的研究结果，我们可以得出结论，NIR-T/BSS 或 NIRS 信号与时频分析的结合为科学开辟了新的前沿，使我们有可能理解和诊断各种与神经退行性和衰老相关的疾病，以改善诊断程序和患者预后。
