Alzaraa Ahmed, Udom Valeri, Mousa Husam, Alzein Abdulhalem, Benhamida Abduljalil, Dalal Neha
Department of General Surgery, Tameside General Hospital, Manchester, UK.
World J Surg Oncol. 2007 Sep 14;5:103. doi: 10.1186/1477-7819-5-103.
Cystic neoplasms of the pancreas comprise 10%-15% of pancreatic cystic lesions, with the serous cystadenoms being the commonest. The association of exocrine and endocrine tumours of the pancreas unrelated to Von Hipple Lindau disease is very rare. Very few cases have been reported in the literature. We present another case of both these tumours in one patient.
A female patient was seen in the surgical clinic for a pain in the right groin. Clinical examination and investigations confirmed a diagnosis of combined endocrine and exocrine tumours of the pancreas. She underwent surgery and is under regular follow-up in the surgical clinic.
Biphasic differentiation of pancreatic stem cell during embryological development could happen and may result in combined endocrine and exocrine tumours of the pancreas. Imaging studies are excellent in diagnosing theses lesions. Surgery has a central role and could be curative.
胰腺囊性肿瘤占胰腺囊性病变的10% - 15%，其中浆液性囊腺瘤最为常见。胰腺外分泌和内分泌肿瘤与冯·希佩尔·林道病无关的关联非常罕见。文献中报道的病例极少。我们在此报告另一例一名患者同时患有这两种肿瘤的病例。
一名女性患者因右腹股沟疼痛就诊于外科门诊。临床检查和各项检查确诊为胰腺内分泌和外分泌联合肿瘤。她接受了手术，目前在外科门诊定期随访。
胰腺干细胞在胚胎发育过程中可能发生双相分化，并可能导致胰腺内分泌和外分泌联合肿瘤。影像学检查在诊断这些病变方面效果极佳。手术起着核心作用，且可能治愈疾病。
