三例胰腺浆液性囊腺瘤和内分泌肿瘤。
Three cases of pancreatic serous cystadenoma and endocrine tumour.
作者信息
Blandamura Stella, Parenti Anna, Famengo Barbara, Canesso Alessandra, Moschino Paolo, Pasquali Claudio, Pizzi Sara, Guzzardo Vincenza, Ninfo Vito
机构信息
Department of Oncological and Surgical Sciences, Section of Pathological Anatomy, University of Padova, Padova, Italy.
出版信息
J Clin Pathol. 2007 Mar;60(3):278-82. doi: 10.1136/jcp.2006.036954. Epub 2006 Apr 27.
AIMS
To report three cases of serous cystadenoma and endocrine tumour in the same pancreas, to review the literature and to evaluate the clinicopathological features of the tumours.
CASES
Three women (71, 57 and 31 years old) were admitted to hospital, two for diseases unrelated to the pancreas and the third for increasing obstructive jaundice in von Hippel-Lindau disease. Preoperative examination showed two distinct lesions in the first patient and only cystic lesions in the other two.
RESULTS
Histological examination of the pancreas showed one serous oligocystic adenoma associated with a benign, well-differentiated endocrine tumour, one serous oligocystic adenoma associated with an endocrine microadenoma, and a von Hippel-Lindau-related cystic neoplasm with a well-differentiated endocrine carcinoma.
CONCLUSIONS
Serous cystadenoma associated with endocrine tumour shows some clinicopathological differences with respect to the two tumours considered separately, and with respect to von Hippel-Lindau-related cases, although there is no convincing evidence at present to justify considering this association as a separate entity.
目的
报告3例胰腺同时存在浆液性囊腺瘤和内分泌肿瘤的病例，回顾相关文献并评估这些肿瘤的临床病理特征。
病例
3名女性（年龄分别为71岁、57岁和31岁）入院，其中2名因与胰腺无关的疾病入院，第3名因von Hippel-Lindau病导致的梗阻性黄疸加重入院。术前检查显示，第1例患者有两个不同的病变，另外两例仅有囊性病变。
结果
胰腺组织学检查显示，1例浆液性少囊性腺瘤合并良性、高分化内分泌肿瘤，1例浆液性少囊性腺瘤合并内分泌微腺瘤，以及1例与von Hippel-Lindau病相关的囊性肿瘤合并高分化内分泌癌。
结论
与内分泌肿瘤相关的浆液性囊腺瘤与分别考虑的这两种肿瘤相比，以及与von Hippel-Lindau病相关的病例相比，表现出一些临床病理差异，尽管目前尚无令人信服的证据证明将这种关联视为一个独立的实体是合理的。
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