Webb Darby, Guttmann Dan, Cawley Patrick, Lubowitz James H
Boise Orthopedic Clinic, Boise, Idaho, USA.
Arthroscopy. 2007 Sep;23(9):1006-11. doi: 10.1016/j.arthro.2007.04.008.
The purpose of this investigation was to evaluate the efficacy, complication rate, and cost of a 1-time interscalene block compared with a continuous infusion of a local anesthetic for postoperative pain relief in patients having arthroscopic shoulder surgery.
After prospective power analysis and institutional review board approval, 56 consecutive patients having arthroscopic shoulder surgery under general anesthesia performed by a single surgeon were randomly assigned to 1 of 2 groups to evaluate postoperative pain control. Group 1 patients received a preoperative interscalene block, and group 2 patients received a subacromial continuous infusion of a local anesthetic (0.5% bupivacaine) via a pain pump for 48 hours postoperatively. Pain was evaluated at 12, 24, 36, and 48 hours and then daily on postoperative days 3 through 7 by use of a visual analog scale included in a patient diary. Patients were provided with 2 "rescue" medication options: ibuprofen and Percocet (Endo Pharmaceuticals, Chadds Ford, PA). The total number of tablets ingested was also evaluated over these same intervals. Total hospital outpatient surgical costs for each group were calculated by dividing total hospital charges by the ratio of annual hospital cost to charges.
No statistically significant differences were identified between the 2 groups with regard to visual analog scale pain scores, medication intake, or cost. Complications did not occur in either group. One patient inadvertently removed the pain pump catheter.
Our results support the null hypothesis. We found no difference between interscalene block versus continuous subacromial infusion of a local anesthetic with regard to efficacy, complication rate, or cost.
Level I, prospective, randomized controlled trial.
本研究旨在评估单次肌间沟阻滞与局部麻醉药持续输注用于肩关节镜手术患者术后镇痛的疗效、并发症发生率及成本。
在进行前瞻性效能分析并获得机构审查委员会批准后,56例由同一位外科医生实施全身麻醉下肩关节镜手术的连续患者被随机分为两组,以评估术后疼痛控制情况。第1组患者接受术前肌间沟阻滞,第2组患者术后通过镇痛泵接受肩峰下局部麻醉药(0.5%布比卡因)持续输注48小时。分别在术后12、24、36和48小时,以及术后第3天至第7天每天使用患者日记中的视觉模拟量表评估疼痛情况。为患者提供两种“解救”药物选择:布洛芬和羟考酮/对乙酰氨基酚片(Endo制药公司,宾夕法尼亚州查兹福特)。在相同时间段内还评估了药物摄入的总片数。通过将总住院费用除以年度医院成本与收费的比率来计算每组的总医院门诊手术成本。
两组在视觉模拟量表疼痛评分、药物摄入或成本方面均未发现统计学上的显著差异。两组均未发生并发症。1例患者意外拔除了镇痛泵导管。
我们的结果支持原假设。我们发现,在疗效、并发症发生率或成本方面,肌间沟阻滞与肩峰下局部麻醉药持续输注之间没有差异。
I级,前瞻性随机对照试验。