Nutman Thomas B
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4, Room B1-03, 4 Center Drive, Bethesda, MD 20892-0425, USA.
Immunol Allergy Clin North Am. 2007 Aug;27(3):529-49. doi: 10.1016/j.iac.2007.07.008.
Hypereosinophilic syndromes (HES) are a group of heterogeneous disorders many of which remain ill-defined. By definition, the HES must be distinguished from other disorders with persistently elevated eosinophilia with a defined cause. Although marked eosinophilia worldwide is most commonly caused by helminth (worm) infections, the diagnostic approach must include noninfectious (nonparasitic) causes of marked eosinophilia as well.
高嗜酸性粒细胞综合征(HES)是一组异质性疾病,其中许多疾病仍定义不清。根据定义,HES必须与其他有明确病因导致嗜酸性粒细胞持续升高的疾病相区分。虽然全球范围内明显的嗜酸性粒细胞增多最常见的原因是蠕虫感染,但诊断方法也必须包括明显嗜酸性粒细胞增多的非感染性(非寄生虫性)病因。