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胃肠道嗜酸性粒细胞增多症

Gastrointestinal eosinophilia.

作者信息

Zuo Li, Rothenberg Marc E

机构信息

Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

出版信息

Immunol Allergy Clin North Am. 2007 Aug;27(3):443-55. doi: 10.1016/j.iac.2007.06.002.

DOI:10.1016/j.iac.2007.06.002
PMID:17868858
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2034402/
Abstract

Gastrointestinal eosinophilia, a broad term for abnormal eosinophil accumulation in the gastrointestinal tract, involves many different disease identities. These diseases include primary eosinophil associated gastrointestinal diseases, gastrointestinal eosinophilia in hypereosinophilic syndrome, and all gastrointestinal eosinophilic states associated with known causes. Each of these diseases has its unique features but there is no absolute boundary between them. All three groups of gastrointestinal eosinophila are described in this article, although the focus is on primary gastrointestinal eosinophilia.

摘要

胃肠道嗜酸性粒细胞增多症是一个用于描述胃肠道中嗜酸性粒细胞异常聚集的宽泛术语,涉及许多不同的疾病实体。这些疾病包括原发性嗜酸性粒细胞相关胃肠道疾病、高嗜酸性粒细胞综合征中的胃肠道嗜酸性粒细胞增多症,以及所有与已知病因相关的胃肠道嗜酸性粒细胞状态。这些疾病中的每一种都有其独特的特征,但它们之间并没有绝对的界限。本文将对这三组胃肠道嗜酸性粒细胞增多症进行描述,不过重点是原发性胃肠道嗜酸性粒细胞增多症。

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本文引用的文献

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Quantity and distribution of eosinophils in the gastrointestinal tract of children.儿童胃肠道中嗜酸性粒细胞的数量与分布
Pediatr Dev Pathol. 2006 May-Jun;9(3):210-8. doi: 10.2350/11-05-0130.1.
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Eosinophils in the esophagus--peptic or allergic eosinophilic esophagitis? Case series of three patients with esophageal eosinophilia.食管中的嗜酸性粒细胞——消化性或过敏性嗜酸性粒细胞性食管炎?3例食管嗜酸性粒细胞增多症患者的病例系列
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The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease.FIP1L1-PDGFRA融合基因与白细胞介素-5协同作用,诱导小鼠嗜酸性粒细胞增多综合征(HES)/慢性嗜酸性粒细胞白血病(CEL)样疾病。
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Inhibition of human interleukin-13-induced respiratory and oesophageal inflammation by anti-human-interleukin-13 antibody (CAT-354).抗人白细胞介素-13抗体(CAT-354)对人白细胞介素-13诱导的呼吸道和食管炎症的抑制作用
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Cytokine expression in healthy and inflamed mucosa: probing the role of eosinophils in the digestive tract.健康和炎症黏膜中的细胞因子表达:探究嗜酸性粒细胞在消化道中的作用
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