Malik Amina I, Huppert Jill S
University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA.
J Pediatr Adolesc Gynecol. 2007 Oct;20(5):275-9. doi: 10.1016/j.jpag.2007.05.007.
To describe (1) the treatment interval for adolescent females with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (GC), or Trichomonas vaginalis (TV); (2) the proportion treated in < or =7 days; and (3) factors influencing the treatment interval.
Charts of sexually active females from an urban teen health center who participated in a larger study and were positive for CT, GC or TV (N = 58) were retrospectively reviewed for dates of treatment, and compared to demographic and symptom data. The treatment interval was defined as days from visit to treatment. CT and/or GC were analyzed together (CT/GC) because presumptive treatment covered both infections, and the diagnostic test (nucleic acid amplification) differed from that of TV (wet mount or culture).
The median treatment interval was 0 days for TV, 5 days for CT/GC, and 3 days for any STI. Overall, 39 (69%) were treated within 7 days of their visit. Those with TV were more likely than those with CT/GC to receive treatment at their initial visit (58% vs. 6%). Genitourinary symptoms increased the odds of treatment in < or =7 days. The treatment interval was significantly shorter for subjects who had their prescriptions phoned to a pharmacy than for those who returned to clinic for treatment (median 2.5 vs. 8 days).
Where presumptive treatment was uncommon, providers were more likely to prescribe same-day therapy to symptomatic patients or those with TV on wet mount. Additional strategies are needed to improve the proportion of adolescent females treated in < or =7 days.
描述（1）沙眼衣原体（CT）、淋病奈瑟菌（GC）或阴道毛滴虫（TV）感染的青春期女性的治疗间隔；（2）在≤7天内接受治疗的比例；（3）影响治疗间隔的因素。
对一家城市青少年健康中心参与一项更大规模研究且CT、GC或TV检测呈阳性的性活跃女性（N = 58）的病历进行回顾性审查，以获取治疗日期，并与人口统计学和症状数据进行比较。治疗间隔定义为从就诊到治疗的天数。CT和/或GC一起分析（CT/GC），因为经验性治疗涵盖了这两种感染，且诊断测试（核酸扩增）与TV（湿片或培养）不同。
TV感染的中位治疗间隔为0天，CT/GC感染为5天，任何性传播感染（STI）为3天。总体而言，39例（69%）在就诊后7天内接受了治疗。TV感染患者比CT/GC感染患者在初次就诊时接受治疗的可能性更高（58%对6%）。泌尿生殖系统症状增加了在≤7天内接受治疗的几率。处方通过电话发送到药房的患者的治疗间隔明显短于返回诊所接受治疗的患者（中位值分别为2.5天和8天）。
在经验性治疗不常见的情况下，医疗服务提供者更有可能为有症状的患者或湿片检查发现TV感染的患者开具当日治疗处方。需要采取其他策略来提高在≤7天内接受治疗的青春期女性的比例。
