Wetzel Caitlin, Tissot Abbigail, Kollar Linda M, Hillard Paula A, Stone Rachel, Kahn Jessica A
University of North Carolina, Chapel Hill, North Carolina, USA.
J Pediatr Adolesc Gynecol. 2007 Oct;20(5):281-7. doi: 10.1016/j.jpag.2006.12.002.
To develop an educational protocol about HPV and Pap tests for adolescents, to evaluate the protocol for understandability and clarity, and to evaluate the protocol for its effectiveness in increasing knowledge about HPV.
In phase 1, investigators and adolescents developed the protocol. In phase 2, adolescents evaluated the protocol qualitatively, investigators evaluated its effectiveness in increasing HPV knowledge in a sample of adolescents, and the protocol was revised. In phase 3, investigators evaluated the effectiveness of the revised protocol in an additional adolescent sample.
Urban, hospital-based teen health center.
A total of 252 adolescent girls and boys in the three study phases.
Pre- and post-protocol knowledge about HPV, measured using a 10- or 11-item scale.
Scores on the HPV knowledge scale increased significantly (P < 0.0001) among adolescents who participated in phases 2 and 3 after they received the protocol. Initial differences in scores based on race, insurance type, and condom use were not noted post-protocol.
The protocol significantly increased knowledge scores about HPV in this population, regardless of sociodemographic characteristics and risk behaviors. Effective, developmentally appropriate educational protocols about HPV and Pap tests are particularly important in clinical settings as cervical cancer screening guidelines evolve, HPV DNA testing is integrated into screening protocols, and HPV vaccines become available. In-depth, one-on-one education about HPV may also prevent adverse psychosocial responses and promote healthy sexual and Pap screening behaviors in adolescents with abnormal HPV or Pap test results.
为青少年制定一份关于人乳头瘤病毒（HPV）和巴氏试验的教育方案，评估该方案的易懂性和清晰度，并评估其在增加HPV知识方面的有效性。
在第1阶段，研究人员和青少年共同制定方案。在第2阶段，青少年对方案进行定性评估，研究人员评估该方案在增加青少年样本中HPV知识方面的有效性，并对方案进行修订。在第3阶段，研究人员在另外一组青少年样本中评估修订后方案的有效性。
城市中以医院为基础的青少年健康中心。
三个研究阶段共有252名青少年女孩和男孩。
使用10项或11项量表测量方案实施前后关于HPV的知识。
参与第2和第3阶段的青少年在接受方案后，HPV知识量表得分显著提高（P < 0.0001）。方案实施后，未发现基于种族、保险类型和避孕套使用情况的得分初始差异。
该方案显著提高了该人群中关于HPV的知识得分，无论其社会人口统计学特征和风险行为如何。随着宫颈癌筛查指南的演变、HPV DNA检测纳入筛查方案以及HPV疫苗的上市，在临床环境中制定有效、适合青少年发育阶段的关于HPV和巴氏试验的教育方案尤为重要。针对HPV进行深入的一对一教育也可能预防不良的心理社会反应，并促进HPV或巴氏试验结果异常的青少年养成健康的性行为和巴氏筛查行为。
