二水焦磷酸钙沉积病：形态学和微量分析特征

Calcium pyrophosphate dihydrate deposition disease: morphological and microanalytical features.

作者信息

Keen C E, Crocker P R, Brady K, Hasan N, Levison D A

机构信息

Department of Histopathology, Lewisham Hospital, London, UK.

出版信息

Histopathology. 1991 Dec;19(6):529-36. doi: 10.1111/j.1365-2559.1991.tb01501.x.

DOI:10.1111/j.1365-2559.1991.tb01501.x

PMID:1786937

Abstract

The light microscopic and polarization appearances of calcium pyrophosphate dihydrate crystal deposits in tissues are reviewed. In routine sections haematoxylinophilic crystalline deposits with a feathery or brush-like pattern are typical of calcium pyrophosphate dihydrate. Short rhomboidal crystals showing positive birefringence are seen on polarization; X-ray microanalytical and infrared spectroscopic data support the specificity of these appearances. The appearances of the crystal deposits in decalcified specimens are also described. We include six cases of calcium pyrophosphate dihydrate deposition within periarticular bone; to the best of our knowledge this has not previously been described.

摘要

本文综述了焦磷酸钙二水合物晶体在组织中的光镜及偏振表现。在常规切片中，焦磷酸钙二水合物典型表现为嗜苏木精的晶体沉积，呈羽毛状或刷状。偏振光下可见短菱形晶体呈正双折射；X射线微分析和红外光谱数据支持这些表现的特异性。文中还描述了脱钙标本中晶体沉积的表现。我们纳入了6例关节周围骨内焦磷酸钙二水合物沉积的病例；据我们所知，此前尚无相关描述。