McCormack James P, Loewen Peter
Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver.
Can Fam Physician. 2007 Aug;53(8):1326-7.
To determine the degree to which current Canadian clinical practice guidelines (CPGs) for common chronic conditions (ie, diabetes, dyslipidemias, hypertension, and osteoporosis) discuss the importance of patients' values and preferences in therapeutic decision making, and provide quantitative information that would allow for comprehensive shared informed decision making.
Retrospective, observational review.
The presence or absence of specific mentions of the importance of incorporating patients' values and preferences into therapeutic decision making; the number and type (relative or absolute) of quantitative descriptions of benefit or harm; the number of interventions for which a means of quantitatively determining the probability that an individual patient will experience an end point without and with implementation of the therapeutic intervention; and the number of descriptions of specific or comparative costs of treatment.
Three of 5 CPGs mentioned that patients' values or preferences should influence treatment decisions. None of the CPGs recommended that benefits and harms of therapies be discussed with patients. Of the 63 quantitative mentions of therapeutic effects of interventions, 81%were presented using relative terms and 19% met our criteria for applicability to decision making for individual patients. Two of the 5 CPGs did not enumerate any harms. Three of the 5 CPGs made no mention of cost.
Five prominent Canadian CPGs paid little attention to the issue of patients' values and preferences in therapeutic decision making, even though these issues are fundamental tenets of evidence-based practice. These 5 CPGs provided limited quantitative information on benefits and harms and therefore could not be used by clinicians to truly involve patients in informed decision making.
确定加拿大当前针对常见慢性病(即糖尿病、血脂异常、高血压和骨质疏松症)的临床实践指南(CPG)在多大程度上讨论了患者价值观和偏好对治疗决策的重要性,并提供能够实现全面共同知情决策的定量信息。
回顾性观察性综述。
是否有关于将患者价值观和偏好纳入治疗决策重要性的具体提及;益处或危害的定量描述的数量和类型(相对或绝对);对于个体患者在不实施和实施治疗干预情况下发生终点事件概率的定量确定方法的干预措施数量;以及治疗的具体或比较成本的描述数量。
5份CPG中有3份提到患者的价值观或偏好应影响治疗决策。没有一份CPG建议与患者讨论治疗的益处和危害。在对干预措施治疗效果的63次定量提及中,81%是用相对术语表述的,19%符合我们适用于个体患者决策的标准。5份CPG中有2份未列举任何危害。5份CPG中有3份未提及成本。
加拿大5份重要的CPG在治疗决策中对患者价值观和偏好问题关注甚少,尽管这些问题是循证实践的基本原则。这5份CPG提供的关于益处和危害的定量信息有限,因此临床医生无法利用它们真正让患者参与知情决策。