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评论:维持体细胞/生殖细胞的区分:一些伦理缺陷。

Commentary: maintaining the somatic/germ-line distinction: some ethical drawbacks.

作者信息

Moseley R

机构信息

Department of Community Health & Family Medicine, College of Medicine, University of Florida, Gainesville 32610.

出版信息

J Med Philos. 1991 Dec;16(6):641-7. doi: 10.1093/jmp/16.6.641.

DOI:10.1093/jmp/16.6.641
PMID:1787392
Abstract

Determinations of the ethical acceptability of genetic therapy have relied on several distinctions in attempts to separate ethically acceptable genetic therapy from those possible therapies that could lead to genetic modifications of future human beings. One distinction that has been proposed is that genetic modifications of human somatic cells is ethically acceptable but that germ-line genetics modifications would be ethically objectionable. This paper examines several serious difficulties which call into question the ethical relevance of a somatic/germ-line distinction.

摘要

对基因治疗伦理可接受性的判定依赖于若干区分,试图将伦理上可接受的基因治疗与那些可能导致未来人类基因改变的潜在治疗方法区分开来。有人提出的一种区分是,对人类体细胞的基因改变在伦理上是可接受的,但生殖系基因改变在伦理上是令人反感的。本文探讨了几个严重的困难,这些困难使体细胞/生殖系区分的伦理相关性受到质疑。

相似文献

1
Commentary: maintaining the somatic/germ-line distinction: some ethical drawbacks.评论:维持体细胞/生殖细胞的区分:一些伦理缺陷。
J Med Philos. 1991 Dec;16(6):641-7. doi: 10.1093/jmp/16.6.641.
2
Ethical issues in manipulating the human germ line.人类生殖系操作中的伦理问题。
J Med Philos. 1991 Dec;16(6):621-39. doi: 10.1093/jmp/16.6.621.
3
Genetic disorders and the ethical status of germ-line gene therapy.遗传疾病与生殖系基因治疗的伦理地位。
J Med Philos. 1991 Dec;16(6):667-83. doi: 10.1093/jmp/16.6.667.
4
Germ-line engineering: a few European voices.生殖系工程:一些欧洲人的观点。
J Med Philos. 1991 Dec;16(6):649-66. doi: 10.1093/jmp/16.6.649.
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Germ-line gene therapy: back to basics.生殖系基因治疗:回归基础。
J Med Philos. 1991 Dec;16(6):587-92. doi: 10.1093/jmp/16.6.587.
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Commentary: how do we think about the ethics of human germ-line genetic therapy?评论:我们如何看待人类生殖系基因治疗的伦理问题?
J Med Philos. 1991 Dec;16(6):613-9. doi: 10.1093/jmp/16.6.613.
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Human gene therapy and slippery slope arguments.人类基因治疗与滑坡论证。
J Med Ethics. 1995 Dec;21(6):350-5. doi: 10.1136/jme.21.6.350.
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What is morally distinctive about genetic engineering?基因工程在道德层面有何独特之处?
Hum Gene Ther. 1990 Winter;1(4):419-24. doi: 10.1089/hum.1990.1.4-419.
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Debunking the slippery slope argument against human germ-line gene therapy.揭穿反对人类生殖系基因治疗的滑坡论证。
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Ethical manipulations: an ethical evaluation of the debate surrounding genetic engineering.伦理操纵:对围绕基因工程的辩论的伦理评估
Hum Gene Ther. 1991 Spring;2(1):71-5. doi: 10.1089/hum.1991.2.1-71.

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The Future of Prenatal Diagnosis and Screening.产前诊断与筛查的未来
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Ethics and germline gene editing.伦理与生殖系基因编辑。
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The ethics of germ line gene manipulation--a five dimensional debate.生殖系基因操纵的伦理——一场五维度的辩论。
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Human gene therapy and the slippery slope argument.人类基因治疗与滑坡论证。
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