Hill D D, Cauley J A, Sheu Y, Bunker C H, Patrick A L, Baker C E, Beckles G L A, Wheeler V W, Zmuda J M
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Osteoporos Int. 2008 Feb;19(2):227-34. doi: 10.1007/s00198-007-0450-9. Epub 2007 Sep 14.
Correlates of BMD were examined in a cross-sectional analysis of men of West African ancestry. BMD, measured at the total hip and the femoral neck subregion, was associated with age, anthropometric, lifestyle, and medical factors in multiple linear regression models. These models explained 25-27% of the variability in total hip and femoral neck BMD, respectively, and 13% of the variability in estimated volumetric BMD.
To examine the correlates of bone mineral density (BMD) in men of West African ancestry.
Two thousand five hundred and one men aged 40 to 93 years were recruited from the Caribbean Island of Tobago. Participants completed a questionnaire and physical examination. We measured hip BMD and body composition, using DXA. Volumetric BMD was estimated as bone mineral apparent density (BMAD).
BMD was 10% and 20% higher in African Caribbean males compared to U.S. non-Hispanic black and white males, respectively. In multiple linear regression models, greater lean mass, history of working on a fishing boat or on a farm, frequent walking, and self-reported diabetes were significantly associated with higher BMD. Fat mass, history of farming, and self-reported hypertension were also associated with higher BMAD. Older age, mixed African ancestry, and history of a fracture were associated with lower BMD and BMAD. Lean body mass explained 20%, 18% and 6% of the variance in BMD at the total hip, femoral neck and BMAD, respectively.
African Caribbean males have the highest BMD on a population level ever reported. Lean mass was the single most important correlate. Variability in BMD/BMAD was also explained by age, mixed African ancestry, anthropometric, lifestyle, and medical factors.
在一项对西非裔男性的横断面分析中，研究了骨密度（BMD）的相关因素。在全髋和股骨颈亚区域测量的BMD，在多元线性回归模型中与年龄、人体测量学、生活方式和医学因素相关。这些模型分别解释了全髋和股骨颈BMD变异性的25%-27%，以及估计体积骨密度变异性的13%。
研究西非裔男性骨矿物质密度（BMD）的相关因素。
从加勒比海多巴哥岛招募了2501名年龄在40至93岁之间的男性。参与者完成了问卷调查和体格检查。我们使用双能X线吸收法（DXA）测量髋部BMD和身体成分。体积骨密度估计为骨矿物质表观密度（BMAD）。
与美国非西班牙裔黑人和白人男性相比，非洲加勒比男性的BMD分别高出10%和20%。在多元线性回归模型中，更大的瘦体重、有在渔船或农场工作的经历、经常步行以及自我报告的糖尿病与更高的BMD显著相关。脂肪量、务农经历和自我报告的高血压也与更高的BMAD相关。年龄较大、混合非洲血统和有骨折史与较低的BMD和BMAD相关。瘦体重分别解释了全髋、股骨颈BMD和BMAD变异性的20%、18%和6%。
非洲加勒比男性在人群水平上拥有有史以来报道的最高BMD。瘦体重是唯一最重要的相关因素。BMD/BMAD的变异性也可由年龄、混合非洲血统、人体测量学、生活方式和医学因素来解释。
