Nam H-S, Shin M-H, Zmuda J M, Leung P C, Barrett-Connor E, Orwoll E S, Cauley J A
Department of Preventive Medicine, Research Institute for Medical Sciences, Chungnam National University College of Medicine, Daejeon, South Korea.
Osteoporos Int. 2010 Dec;21(12):2115-23. doi: 10.1007/s00198-010-1188-3. Epub 2010 Mar 4.
BMD was compared across race/ethnic groups. There were substantial race/ethnic differences in BMD even within African or Asian origin. Additional adjustment for body size greatly attenuated or reversed the differences between US Caucasian men vs Asian men. It illustrates the role of body size on the difference between these groups.
There is insufficient epidemiologic information about men's bone mineral density (BMD) levels across race/ethnic groups and geographic locations.
In a cross-sectional design, we compared BMD in older men across seven race/ethnic groups in four countries. Femoral neck, total hip, and lumbar spine BMD were measured in men (age 65 to 78 years) from the Osteoporotic Fractures in Men (MrOS) Study (4,074 Caucasian, 208 African-American, 157 Asian, and 116 Hispanic men in USA), Tobago Bone Health Study (422 Afro-Caribbean men), MrOS Hong Kong Study (1,747 Hong Kong Chinese men), and the Namwon Study (1,079 South Korean men). BMD was corrected according to the cross-site calibration results for all scanners.
When compared with US Caucasian men, Afro-Caribbean and African-American men had, respectively, 8-20% and 6-11% higher age-adjusted mean BMD at all three bone sites. Hip BMD was similar in US Caucasian and Hispanic men, US Asian, Hong Kong Chinese, and Korean men had 3-14% lower BMD at all bone sites except femoral neck in Korean men. Additional adjustment for weight and height greatly attenuated or reversed the differences between US Caucasian men vs Asian men including US Asian, Hong Kong Chinese, and South Korean men. Among Asian groups, Korean men had higher femoral neck BMD and lower total hip BMD.
These findings show substantial race/ethnic differences in BMD even within African or Asian origin and illustrate the important role of body size on the difference between Asian men and others.
对不同种族/族裔群体的骨密度（BMD）进行了比较。即使在非洲裔或亚裔群体内部，BMD也存在显著的种族/族裔差异。对体型进行额外调整后，美国白种男性与亚洲男性之间的差异大幅减弱或逆转。这说明了体型在这些群体差异中所起的作用。
关于不同种族/族裔群体以及不同地理位置男性的骨矿物质密度（BMD）水平，流行病学信息不足。
采用横断面设计，我们比较了四个国家中七个种族/族裔群体老年男性的BMD。对来自男性骨质疏松性骨折（MrOS）研究（美国4074名白种人、208名非裔美国人、157名亚洲人和116名西班牙裔男性）、多巴哥骨健康研究（422名非洲加勒比男性）、MrOS香港研究（1747名中国香港男性）和南原研究（1079名韩国男性）的65至78岁男性测量了股骨颈、全髋和腰椎的BMD。根据所有扫描仪的跨站点校准结果对BMD进行了校正。
与美国白种男性相比，非洲加勒比和非裔美国男性在所有三个骨部位的年龄调整后平均BMD分别高8 - 20%和6 - 11%。美国白种男性和西班牙裔男性的髋部BMD相似，美国亚裔、中国香港和韩国男性在所有骨部位（韩国男性的股骨颈除外）的BMD低3 - 14%。对体重和身高进行额外调整后，美国白种男性与包括美国亚裔、中国香港和韩国男性在内的亚洲男性之间的差异大幅减弱或逆转。在亚洲群体中，韩国男性的股骨颈BMD较高，全髋BMD较低。
这些发现表明，即使在非洲裔或亚裔群体内部，BMD也存在显著的种族/族裔差异，并说明了体型在亚洲男性与其他男性差异中所起的重要作用。
