Lin Pei-Ying, Nhung Bui Thi, Khan Nguyen Cong, Sarukura Nobuko, Kunii Daisuke, Sakai Tohru, Kassus Afework, Yamamoto Shigeru
Department of International Public Health Nutrition, Institute of Health Biosciences, The University of Tokushima, Tokushima, Japan.
J Nutr Sci Vitaminol (Tokyo). 2007 Jun;53(3):247-52. doi: 10.3177/jnsv.53.247.
To elucidate the effect of a typical Vietnamese diet including a high content of white rice on postprandial blood glucose levels, the present study was designed. Thirty healthy female subjects with a similar body mass index, 10 each in their twenties, forties and sixties, were recruited. Four meals with a similar protein energy percentage (13-15%) but different energy ratios of fat and carbohydrate (FC ratio) and vegetable contents were provided by cross-over design. Meal A was designed according to the commonly consumed diet in Vietnam. The FC ratio was 14:71 and 84 g of carbohydrate was from rice. Meal B contained carbohydrate in a lower ratio than meal A by fat replacement and its FC ratio was 30:57. Meal C was similar to meal A except lacking vegetables. The energy of meal A, B and C was about 2.1 MJ. Meal D was designed to match the amount of carbohydrate and fat within A and B, respectively. The FC ratio of meal D was 26:61 and the energy was about 2.4 MJ. Fasting blood glucose was measured before consumption of a test meal. Postprandial blood glucose was measured every 30 min for 2 h. Areas under the curve (AUC) were calculated to compare the glycemic response among the four test meals. There was no significant difference in AUC among the four test meals in the subjects in their twenties. In the subjects in their forties, the AUC of meal A tended to be lower than that of meal C (p = 0.07). In the subjects in their sixties, the AUC of meal A was significantly higher than that of meal B (p < 0.001). Glycemic responses showed a significant relationship with age (r = 0.26, p < 0.01); however, there was no association between glycemic responses and BMI (p = 0.20). Dietary fat ratios were inversely associated with glycemic responses (r = -0.28, p < 0.01). In conclusion, the diet with about 70% energy from carbohydrate which is commonly consumed by Vietnamese may increase glycemic response, especially in elderly people and dietary vegetables may be beneficial to prevent such an increase in glycemic response.
为阐明典型的越南饮食(包括高含量白米饭)对餐后血糖水平的影响,开展了本研究。招募了30名体重指数相近的健康女性受试者,分别为20多岁、40多岁和60多岁各10名。通过交叉设计提供四餐,蛋白质能量百分比相似(13 - 15%),但脂肪与碳水化合物能量比(FC比)及蔬菜含量不同。餐A按照越南常见饮食设计。FC比为14:71,84克碳水化合物来自大米。餐B通过脂肪替代使碳水化合物比例低于餐A,其FC比为30:57。餐C与餐A相似,但不含蔬菜。餐A、B和C的能量约为2.1兆焦。餐D设计为分别与餐A和B中的碳水化合物和脂肪量匹配。餐D的FC比为26:61,能量约为2.4兆焦。在食用试验餐之前测量空腹血糖。餐后每30分钟测量血糖,共测量2小时。计算曲线下面积(AUC)以比较四餐试验餐之间的血糖反应。20多岁的受试者中,四餐试验餐的AUC无显著差异。40多岁的受试者中,餐A的AUC倾向于低于餐C(p = 0.07)。60多岁的受试者中,餐A的AUC显著高于餐B(p < 0.001)。血糖反应与年龄呈显著相关(r = 0.26,p < 0.01);然而,血糖反应与体重指数之间无关联(p = 0.20)。膳食脂肪比例与血糖反应呈负相关(r = -0.28,p < 0.01)。总之,越南人常食用的约70%能量来自碳水化合物的饮食可能会增加血糖反应,尤其是在老年人中,而膳食中的蔬菜可能有助于防止血糖反应的这种增加。