Hashemi Seyed Mehdi, Hashemi-Malayeri Bijan, Raisali Gholamreza, Shokrani Parvaneh, Sharafi Ali Akbar, Jafarizadeh Mansour
Department of Medical Physics, Tarbiat Modares University, PO Box 14115-151, Tehran, Iran.
Radiat Prot Dosimetry. 2008;128(3):359-62. doi: 10.1093/rpd/ncm421. Epub 2007 Sep 17.
High-energy linear accelerators (linacs) have several advantages, including low skin doses and high dose rates at deep-seated tumours. But, at energies more than 8 MeV, photonuclear reactions produce neutron contamination around the therapeutic beam, which may induce secondary malignancies. In spite of improvements achieved in medical linac designs, many countries still use conventional (non-intensity-modulated radiotherapy) linacs. Hence, in these conventional machines, fitting the beam over the treatment volume may require using blocks. Therefore, the effect of these devices on neutron production of linacs needs to be studied. The aim of this study was to investigate the effect of field shaping blocks on photoneutron dose in the treatment plane for two high-energy medical linacs. Two medical linacs, a Saturn 43 (25 MeV) and an Elekta SL 75/25 (18 MeV), were studied. Polycarbonate (PC) films were used to measure the fluence of photoneutrons produced by these linacs. After electrochemical etching of the PC films, the neutron dose equivalent was calculated at the isocentre and 50 cm away from the isocentre. It was noted that by increasing the distance from the centre of the X-ray beam towards the periphery, the photoneutron dose equivalent decreases rapidly for both the open and blocked fields. Increasing the energy of the photons causes an increase in the amount of photoneutron dose equivalent. At 25 MeV photon energy, the lead blocks cause a meaningful increase in the dose equivalent of photoneutrons. In this research, a 30% increase was seen in neutron dose contribution to central axis dose at the isocentre of a 25 MeV irregular field shaped by lead blocks. It is concluded that lead blocks must be considered as a source of photoneutron production when treating irregular fields with high-energy photons.
高能直线加速器(直线加速器)具有若干优点,包括皮肤剂量低以及对深部肿瘤的高剂量率。但是,在能量超过8兆电子伏时,光核反应会在治疗束周围产生中子污染,这可能诱发继发性恶性肿瘤。尽管医用直线加速器设计已有改进,但许多国家仍在使用传统的(非调强放射治疗)直线加速器。因此,在这些传统机器中,将射束适配到治疗体积上可能需要使用挡块。所以,需要研究这些装置对直线加速器中子产生的影响。本研究的目的是调查两种高能医用直线加速器的射野成形挡块对治疗平面内光中子剂量的影响。研究了两台医用直线加速器,一台Saturn 43(25兆电子伏)和一台医科达SL 75/25(18兆电子伏)。使用聚碳酸酯(PC)膜来测量这些直线加速器产生的光中子注量。对PC膜进行电化学蚀刻后,在等中心和距等中心50厘米处计算中子剂量当量。注意到,对于开放野和挡块野,随着离X射线束中心向周边距离的增加,光中子剂量当量迅速降低。光子能量增加会导致光中子剂量当量增加。在25兆电子伏光子能量下,铅挡块会使光中子剂量当量有显著增加。在本研究中,由铅挡块成形的25兆电子伏不规则射野等中心处,中子剂量对中心轴剂量的贡献增加了30%。得出的结论是,在用高能光子治疗不规则射野时,必须将铅挡块视为光中子产生源。