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[细菌炎症在儿童声门下喉炎中的作用]

[The role of the bacterial inflammation in subglottic laryngitis in children].

作者信息

Zielnik-Jurkiewicz Beata

机构信息

Oddział Otolaryngologiczny Szpitala Dzieciecego SZPZOZ w Warszawie.

出版信息

Pol Merkur Lekarski. 2005 Feb;18(104):141-5.

PMID:17877117
Abstract

The aim of this study is to assess the impact of some selected bacteriological factors on the occurrence of subglottic laryngitis in children. The research covered 72 children hospitalized in the Children's Hospital in Warsaw with the following symptoms: dry barking cough, stridor, inspiratory dyspnoea with the participation of auxiliary respiratory muscles, agitation and change of colour of skin. Subglottic laryngitis is one of the acute children's diseases, directly caused by a violently growing odema of the subglottic area. The disease constitutes 5-8% of all severe airways inflammations and states that subglottic laryngitis is responsible for 6.5% off all lower airways inflammation cases. Based on preliminary examinations, the patients were divided into two groups--one of them composed of 41 patients with simultaneous atopy, the other--of 31 patients with no atopy symptoms. The examination of each patient included subjective, objective (pediatric and laryngological) and auxiliary (primary-blood cell count, OB and specialized-bacteriological tests) examinations. Own research showed that out of 72 patients with subglottic laryngitis 56.95% had bacterial symptoms. 90.32% in non atopic group have higher NBT test, in atopic children it was 39.02%. We observed that 50.51% of the patients suffering from subglottic laryngitis had an inflammation of upper airways (otitis media, rhinitis, pharyngitis) and 13.89% of lower respiratory tract (bronchitis, pneumonitis). Many authors incline to say that bacteria may be a conductive factor for subglottic laryngitis to develop. However, many factors seem to suggest that the occurrence and symptoms of subglottic laryngitis are primarily caused by the reaction to an infection. The impact of bacteria onto the etiopathogenesis of subglottic laryngitis has been discussed for many years. Some experts are of the opinion that the disease develops on the bacteriologic background.

摘要

本研究的目的是评估某些特定细菌学因素对儿童声门下喉炎发病的影响。该研究涵盖了72名在华沙儿童医院住院的儿童,他们有以下症状:犬吠样干咳、喘鸣、伴有辅助呼吸肌参与的吸气性呼吸困难、烦躁不安及皮肤颜色改变。声门下喉炎是儿童急性疾病之一,直接由声门下区域急剧肿胀引起。该疾病占所有严重气道炎症的5 - 8%,并指出声门下喉炎占所有下呼吸道炎症病例的6.5%。基于初步检查,患者被分为两组——一组由41名同时患有特应性疾病的患者组成,另一组由31名无特应性症状的患者组成。对每位患者的检查包括主观、客观(儿科和喉科)及辅助(血常规、OB及专门的细菌学检测)检查。我们自己的研究表明,在72名声门下喉炎患者中,56.95%有细菌感染症状。非特应性组中90.32%的患者中性粒细胞杀菌功能检测(NBT)结果较高,在特应性儿童中这一比例为39.02%。我们观察到,50.51%的声门下喉炎患者有上呼吸道炎症(中耳炎、鼻炎、咽炎),13.89%有下呼吸道炎症(支气管炎、肺炎)。许多作者倾向于认为细菌可能是声门下喉炎发病的一个促成因素。然而,许多因素似乎表明,声门下喉炎的发生和症状主要是由对感染的反应引起的。细菌对声门下喉炎发病机制的影响已被讨论多年。一些专家认为该疾病是在细菌学背景下发展的。

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