Teng Wei-yu, Wang Hai-long, Shi Jing-pu, Fu Ling-yu, Li Hui, Dong Wei, Dong Ya-luo, Zhou Bo, Zhao Feng, Wang Wen-li
Department of Neurology, The First Affiliated Hospital of Chinese Medical University, Shenyang 110001, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2007 May;28(5):441-4.
To investigate the influencing factors on cerebral stroke in Zhangwu county, Liaoning province, a region with high hypertension prevalence rate.
By cluster sampling method, 5208 adults ( > 18y. ) from 11 villages of 6 towns were registered. General information, common risk factors of cerebral stroke about these persons was recorded. Blood pressure together with several biochemistry indicators was determined. Data were analyzed by SPSS 10.0 software.
Standardized prevalence of cerebral stroke in this region was 3.10%, and the difference between males and females was significant. Prevalence rate was increasing with age. Multiple-factor analysis revealed that the incidence rate of cerebral stroke was related to high blood pressure, high diastolic pressure, pulse pressure, age, high-density lipoprotein cholesterol (HDL-C) and low-DL-C (LDL-C) level with OR values of 95% CI as 2.958 (1.783-4.907), 2.803 (1.934-4.062), 1.154 (1.056-1.261), 1.080 (1.063-1.097), 0.390 (0.235-0.647) and 1.422 (1.008-2.006) respectively.
High blood pressure, in particular high diastolic pressure, pulse pressure and LDL-C level were main risk factors of cerebral stroke in Zhangwu countryside. However, HDL-C level was a protective factor. No new risk factors were discovered.
在辽宁省彰武县这个高血压患病率较高的地区，调查影响脑卒中的因素。
采用整群抽样方法，登记了来自6个镇11个村的5208名成年人（>18岁）。记录了这些人的一般信息、脑卒中的常见危险因素。测定了血压及多项生化指标。数据用SPSS 10.0软件进行分析。
该地区脑卒中标准化患病率为3.10%，男女之间差异有统计学意义。患病率随年龄增长而升高。多因素分析显示，脑卒中发病率与高血压、舒张压高、脉压、年龄、高密度脂蛋白胆固醇（HDL-C）及低密度脂蛋白胆固醇（LDL-C）水平有关，其比值比（OR）及95%可信区间（CI）分别为2.958（1.783～4.907）、2.803（1.934～4.062）、1.154（1.056～1.261）、1.080（1.063～1.097）、0.390（0.235～0.647）和1.422（1.008～2.006）。
高血压，尤其是舒张压高、脉压及LDL-C水平是彰武农村地区脑卒中的主要危险因素。然而，HDL-C水平是一个保护因素。未发现新的危险因素。
