Miyakoshi Naohisa, Shimada Yoichi, Kasukawa Yuji, Ando Shigeru
Division of Orthopedic Surgery, Department of Neuro and Locomotor Science, Akita University School of Medicine, Akita, Japan.
J Neurosurg Spine. 2007 Sep;7(3):362-5. doi: 10.3171/SPI-07/09/362.
Tumoral calcinosis is a rare disorder that most often occurs in periarticular regions of the extremities. Here, the authors report on an extremely rare case of idiopathic intraspinal tumoral calcinosis of the cervical spine. This 54-year-old man presented with a 2-week history of progressive cervical myelopathy. Results of magnetic resonance imaging and computed tomography myelography of the cervical spine revealed an intraspinal calcified mass lesion posterior to the spinal cord at the C3-4 level, resulting in marked spinal cord compression. Spinal cord decompression and en bloc resection of the mass lesion were performed via a C-2 laminoplasty and C3-4 laminectomy. The mass was localized in the dura mater. Histologically, the lesion consisted of numerous nodules with amorphous calcified materials and a florid proliferation of multinucleated giant cells; that is, its histological characteristics were identical to those of tumoral calcinosis. The symptoms disappeared completely after surgery. In all previously reported cases of cervical tumoral calcinosis, the lesion was located in the paraspinal soft tissue, with bone and facet joint involvement. The present case is the first reported instance of cervical tumoral calcinosis localized only in the spinal canal.
肿瘤性钙化是一种罕见的疾病，最常发生于四肢关节周围区域。在此，作者报告了一例极其罕见的颈椎特发性椎管内肿瘤性钙化病例。该54岁男性患者有2周进行性颈髓病病史。颈椎磁共振成像和计算机断层扫描脊髓造影结果显示，在C3 - 4水平脊髓后方有一椎管内钙化肿块病变，导致明显的脊髓受压。通过C - 2椎板成形术和C3 - 4椎板切除术进行脊髓减压并整块切除肿块病变。肿块位于硬脑膜。组织学上，病变由大量含有无定形钙化物质的结节和多核巨细胞的活跃增殖组成；也就是说，其组织学特征与肿瘤性钙化相同。术后症状完全消失。在所有先前报道的颈椎肿瘤性钙化病例中，病变位于椎旁软组织，伴有骨骼和小关节受累。本病例是首次报道的仅局限于椎管内的颈椎肿瘤性钙化病例。
