Matsukado K, Amano T, Itou O, Yuhi F, Nagata S
Department of Neurosurgery, Iizuka Hospital, Iizuka, Fukuoka, Japan.
Neurol Med Chir (Tokyo). 2001 Aug;41(8):411-4. doi: 10.2176/nmc.41.411.
A 54-year-old woman with chronic renal failure presented with tumoral calcinosis manifesting as progressive radiculomyelopathy. Magnetic resonance imaging revealed a spinal epidural mass in the C-2 to C-4 levels. The clinical and radiological findings suggested malignant tumor. Resection of the lesion was performed with total C-2 laminectomy and C-3 and C-4 laminoplasty. The symptoms totally disappeared after surgery. The histological diagnosis was tumoral calcinosis. Tumoral calcinosis is a rare tumoral calcium pyrophosphate dihydrate crystal deposition disease which presents as periarticular soft tissue calcification. Tumoral calcinosis should be considered in patients with a mass lesion involving the upper cervical spine and associated with metabolic abnormalities. Surgical excision is the treatment of choice, because this is completely curative without known recurrence.
一名54岁的慢性肾衰竭女性患者,表现为肿瘤性钙化,呈进行性神经根脊髓病。磁共振成像显示C2至C4水平有脊髓硬膜外肿块。临床和影像学表现提示为恶性肿瘤。通过C2全椎板切除术及C3和C4椎板成形术对病变进行了切除。术后症状完全消失。组织学诊断为肿瘤性钙化。肿瘤性钙化是一种罕见的肿瘤性焦磷酸钙二水合物晶体沉积病,表现为关节周围软组织钙化。对于涉及上颈椎且伴有代谢异常的肿块病变患者,应考虑肿瘤性钙化。手术切除是首选治疗方法,因为其可完全治愈且无已知复发情况。